PubMed ID:
18599322
Public Release Type:
Journal
Publication Year: 2009
Affiliation: Department of Molecular Medicine and Surgery, Rolf Luft Center for Diabetes Research, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
DOI:
https://doi.org/10.1016/j.jdiacomp.2008.05.004
Authors:
Efendic S,
Ma J,
Zhang D,
Gu HF,
Brismar K
Studies:
The Genetics of Kidneys in Diabetes
The adiponectin promoter single nucleotide polymorphism (SNP) -11391G/A is found to be associated with nephropathy in type 1 diabetic (T1D) patients among Danish, but not French, Finnish, and Swedish populations. In the present study, we identified the binding sites for transcriptional factors in the adiponectin promoter region and also evaluated the association between adiponectin promoter polymorphisms and diabetic nephropathy (DN) in T1D patients.