PubMed ID:
18505543
Public Release Type:
Journal
Publication Year: 2008
Affiliation: Rolf Luft Center for Diabetes Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden. jun.ma@ki.se
DOI:
https://doi.org/10.1186/1471-2350-9-47
Authors:
Brismar K,
Efendic S,
Gu HF,
Ma J,
Zhang D
Studies:
The Genetics of Kidneys in Diabetes
The ICAM-1 gene is a strong positional and biological candidate for susceptibility to the development of T1D and DN. We have recently demonstrated that SNP rs5498(E469K) confers susceptibility to the development of T1D and might be associated with DN in Swedish Caucasians. The present study aimed to further evaluate the association between the ICAM-1 genetic polymorphisms and DN.