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Publication Information

PubMed ID
Public Release Type
Journal
Publication Year
2008
Affiliation
Boston University, School of Medicine, Renal Section, EBRC 504, 650 Albany St, Boston, Massachusetts 02118, USA. ldember@bu.edu
Authors
Adams S, Allon M, Arrow AW, Banqero B, Beck G, Beck GJ, Berkoben M, Berkowitz A, Besarab A, Bi S, Braden G, Braden GL, Cantaffa T, Casey B, Chertow G, Clagett P, Coyne D, Creaghan R, Cyr-Alves H, Daeihagh P, Darras F, Davidson I, Davidson IJ, Deep J, Delmez J, Delmez JA, Dember L, Dember LM, Dialysis Access Consortium Study Group, Diener-West M, Dixon B, Dixon BS, Dolmatch B, DuPage K, Egbert P, Feldman H, Feldman HI, Fenves A, Franzwa B, Freedman S, Garrison K, Gassman J, Gassman JJ, Gitter K, Grant C, Greenberg A, Greene T, Hawley M, Himmelfarb J, Hoballah J, Holmberg E, Hoosier T, Hu B, Hunsicker L, Ikizler T, Ikizler TA, Kane J, Katz D, Kaufman J, Kaufman JS, Ketel B, Kovalik E, Kresowik T, Kusek J, Kusek JW, Lauer A, Lawson J, LeSage P, Levin N, Lightfoot T, Littmon L, Liu A, Lluka B, Lockhart M, Louis T, Mauck V, McBride D, McClellan W, Meyers C, Meyers CM, Middleton J, Nathan R, Newsome J, Pearl G, Pflederer T, Pyszka L, Quarles A, Quinones H, Radeva M, Radeva MK, Rayhill S, Robbin M, Rocco M, Rocco MV, Rothstein M, Ryan M, Saxena R, Schumm D, Schwab S, Sharp W, Shenoy S, Stehman-Breen C, Thompson J, Toto R, Tuason L, Tuttle A, Valentine J, Vazquez M, Vazquez MA, Violette R, Weiss B, Welch K, Whiting J, Windus D, Wu Y, Ying C
Studies
Citation
Dember LM, Beck GJ, Allon M, Delmez JA, Dixon BS, Greenberg A, Himmelfarb J, Vazquez MA, Gassman JJ, Greene T, Radeva MK, Braden GL, Ikizler TA, Rocco MV, Davidson IJ, Kaufman JS, Meyers CM, Kusek JW, Feldman HI, Dialysis Access Consortium Study Group. Effect of clopidogrel on early failure of arteriovenous fistulas for hemodialysis: a randomized controlled trial. JAMA 2008 May 14;299(18):2164-71.

Abstract

The arteriovenous fistula is the preferred type of vascular access for hemodialysis because of lower thrombosis and infection rates and lower health care expenditures compared with synthetic grafts or central venous catheters. Early failure of fistulas due to thrombosis or inadequate maturation is a barrier to increasing the prevalence of fistulas among patients treated with hemodialysis. Small, inconclusive trials have suggested that antiplatelet agents may reduce thrombosis of new fistulas.