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Publication Information
Affiliation
Department of Internal Medicine, University of Texas Southwestern Medical Center, 5959 Harry Hines Boulevard, Dallas, TX 75390, USA.
Authors
Acute Liver Failure Study Group, Avant L, Balko JA, Barakat F, Bernard T, Blei AT, Brown R Jr, Campbell M, Casson D, Chung R, Coultrup S, Crippin JS, Davern TJ, Do H, Emre S, Fontana RJ, Fuller D, Gerstle L, Gottstein J, Groettum C, Han S, Harrison ME, Hassenein T, Hay JE, Huntley N, Hynan LS, Ingram K, Khan AI, Koff JM, Lalani E, Larson AM, Lee WM, McCashland TM, McGuire B, Misra C, Morton D, Munoz S, Murray N, Murray NG, Orsulak P, Partovi K, Peacock V, Pezzia C, Polson J, Prosser C, Reddy R, Reisch JS, Reuben A, Rossaro L, Rush R, Salvatori J, Satyanarayana R, Schilsky M, Schwartz J, Senkbeil L, Shakil AO, Smith A, Stravitz T, Taylor W, Welch S, Wians FH Jr, Zaman A
Studies
Citation
Polson J, Wians FH Jr, Orsulak P, Fuller D, Murray NG, Koff JM, Khan AI, Balko JA, Hynan LS, Lee WM, Acute Liver Failure Study Group. False positive acetaminophen concentrations in patients with liver injury. Clin Chim Acta 2008 May;391(1-2):24-30. Epub 2008 Jan 26.Abstract
Acetaminophen toxicity is the most common form of acute liver failure in the U.S. After acetaminophen overdoses, quantitation of plasma acetaminophen can aid in predicting severity of injury. However, recent case reports have suggested that acetaminophen concentrations may be falsely increased in the presence of hyperbilirubinemia.