NIDDK Central Repository - Variants in the plasmacytoma variant translocation gene (PVT1) are associated with end-stage renal disease attributed to type 1 diabetes.

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NIDDK Central Repository

Publication Information

DOI

10.2337/db07-0675

PubMed ID

17881614

Public Release Type

Journal

Publication Year

2007

Affiliation

Translational Genomics Research Institute, 445 North Fifth St., Phoenix, AZ 85004, USA.

Authors

Bowen D, Kingsley C, Millis MP, Watanabe RM, Wolford JK

Studies

GoKinD

Citation

Millis MP, Bowen D, Kingsley C, Watanabe RM, Wolford JK. Variants in the plasmacytoma variant translocation gene (PVT1) are associated with end-stage renal disease attributed to type 1 diabetes. Diabetes 2007 Dec;56(12):3027-32. Epub 2007 Sep 19.

Abstract

End-stage renal disease (ESRD) attributed to diabetes is strongly dependent on genetic factors. We previously reported association between variants in the plasmacytoma variant translocation gene (PVT1) and ESRD attributed to type 2 diabetes in Pima Indians. The objective of this study was to evaluate the extent to which these variants mediate susceptibility in other populations.