NIDDK Central Repository - Assessment of reliability and validity of IBD phenotyping within the National Institutes of Diabetes and Digestive and Kidney Diseases (NIDDK) IBD Genetics Consortium (IBDGC).

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NIDDK Central Repository

Publication Information

DOI

10.1002/ibd.20144

PubMed ID

17427244

Public Release Type

Journal

Publication Year

2007

Affiliation

Johns Hopkins University Meyerhoff Inflammatory Bowel Disease Center, Baltimore MD, USA.

Authors

Achkar JP, Bitton A, Brant SR, Bromfield GP, Cho JH, Dassopoulos T, Duerr RH, Elkadri A, Franchimont D, Gregory FJ, Griffiths A, Harrell LE, Kane SV, Nguyen GC, Regueiro M, Rioux JD, Schumm LP, Siemanowski B, Silverberg MS, Steinhart AH, Taylor KD, Torres EA, Wu Y

Studies

IBD

Citation

Dassopoulos T, Nguyen GC, Bitton A, Bromfield GP, Schumm LP, Wu Y, Elkadri A, Regueiro M, Siemanowski B, Torres EA, Gregory FJ, Kane SV, Harrell LE, Franchimont D, Achkar JP, Griffiths A, Brant SR, Rioux JD, Taylor KD, Duerr RH, Silverberg MS, Cho JH, Steinhart AH. Assessment of reliability and validity of IBD phenotyping within the National Institutes of Diabetes and Digestive and Kidney Diseases (NIDDK) IBD Genetics Consortium (IBDGC). Inflamm Bowel Dis 2007 Aug;13(8):975-83.

Abstract

The NIDDK IBD Genetics Consortium (IBDGC) collects DNA and phenotypic data from inflammatory bowel disease (IBD) subjects to provide a resource for genetic studies. No previous studies have been performed on the reliability and validity of phenotypic determinations in either Crohn's disease (CD) or ulcerative colitis (UC) using primary records. Our aim was to determine the reliability and validity of these phenotypic assessments.