PubMed ID:
16996806
Public Release Type:
Journal
Publication Year: 2006
Affiliation: GI Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.
DOI:
https://doi.org/10.1016/j.cgh.2006.07.014
Authors:
Chung RT,
Lee WM,
Acute Liver Failure Study Group,
Davern T,
Hassanein T,
Hay JE,
Murray NG,
Rutherford A
Studies:
Acute Liver Failure Study Group: Adult Acute Liver Failure Study
Diabetes and obesity affect development of nonalcoholic fatty liver disease. Nonalcoholic fatty liver disease increases susceptibility to hepatic injury and limits regenerative capacity, which might increase adverse outcomes in acute liver failure. There is no difference in the prevalence of diabetes in acute liver failure patients when compared with the general population, but no large studies have examined the relationship of obesity to incidence or outcome of acute liver failure.