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Publication Information
Affiliation
Department of Gastroenterology, VU University Medical Centre, Amsterdam, The Netherlands.
Authors
Annese V, Bitton A, Crusius JB, Curley CR, Daly MJ, Fisher SA, Forbes A, Hunt KA, Latiano A, Linskens RK, Mathew CG, Monsuur AJ, Onnie CM, Playford RJ, Prescott NJ, Rioux JD, Sanderson J, Silverberg MS, Steinhart AH, Strachan DP, van Bodegraven AA, van Heel DA, Wijmenga C
Studies
Citation
van Bodegraven AA, Curley CR, Hunt KA, Monsuur AJ, Linskens RK, Onnie CM, Crusius JB, Annese V, Latiano A, Silverberg MS, Bitton A, Fisher SA, Steinhart AH, Forbes A, Sanderson J, Prescott NJ, Strachan DP, Playford RJ, Mathew CG, Wijmenga C, Daly MJ, Rioux JD, van Heel DA. Genetic variation in myosin IXB is associated with ulcerative colitis. Gastroenterology 2006 Dec;131(6):1768-74. Epub 2006 Sep 8.Abstract
Common germline genetic variation in the 3' region of myosin IXB (MYO9B) has been associated recently with susceptibility to celiac disease, with a hypothesis that MYO9B variants might influence intestinal permeability. These findings suggested the current study investigating a possible further role for MYO9B variation in inflammatory bowel disease.