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Publication Information
Affiliation
Section of Endocrinology and Diabetes, University of Oklahoma Health Sciences Center, WP1345, Oklahoma City, OK 73104, USA.
Authors
Aston CE, Baynes JW, DCCT/EDIC Research Group, Jenkins AJ, Lyons TJ, McGee D, McKnight JA, Orchard TJ, Peng YG, Shaw JN, Silvers N, Sochaski MA, Thorpe SR, Yu Y
Studies
Citation
Yu Y, Thorpe SR, Jenkins AJ, Shaw JN, Sochaski MA, McGee D, Aston CE, Orchard TJ, Silvers N, Peng YG, McKnight JA, Baynes JW, Lyons TJ, DCCT/EDIC Research Group. Advanced glycation end-products and methionine sulphoxide in skin collagen of patients with type 1 diabetes. Diabetologia 2006 Oct;49(10):2488-98. Epub 2006 Aug 29.Abstract
We determined whether oxidative damage in collagen is increased in (1) patients with diabetes; (2) patients with diabetic complications; and (3) subjects from the Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) study, with comparison of subjects from the former standard vs intensive treatment groups 4 years after DCCT completion.