NIDDK Central Repository - Specific human leukocyte antigen DQ influence on expression of antiislet autoantibodies and progression to type 1 diabetes.

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NIDDK Central Repository

Publication Information

DOI

10.1210/jc.2005-1695

PubMed ID

16464953

Public Release Type

Journal

Publication Year

2006

Affiliation

Department of Endocrinology, University Clinic of Navarra, 31008 Pamplona, Spain.

Authors

Babu S, Cuthbertson D, Diabetes Prevention Trial Type 1 Study Group, Eisenbarth GS, Greenbaum C, Krischer JP, Orban T, Palmer JP, Redondo MJ, Schatz D, Yu L, Zeidler A

Studies

DPT-1

Citation

Redondo MJ, Babu S, Zeidler A, Orban T, Yu L, Greenbaum C, Palmer JP, Cuthbertson D, Eisenbarth GS, Krischer JP, Schatz D, Diabetes Prevention Trial Type 1 Study Group. Specific human leukocyte antigen DQ influence on expression of antiislet autoantibodies and progression to type 1 diabetes. J Clin Endocrinol Metab 2006 May;91(5):1705-13. Epub 2006 Feb 7.

Abstract

Human leukocyte antigen (HLA) DQ haplotypes have the strongest genetic association with type 1 diabetes (T1DM) risk.