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PubMed ID:
15260927
Public Release Type:
Journal
Publication Year: 2004
Affiliation: Department of Urology, Weill Medical College of Cornell University, 1300 York Avenue, New York, NY 10021, USA.
DOI:
https://doi.org/10.1007/s11934-004-0050-6
Authors:
Sandhu JS,
Te AE
Studies:
Medical Therapy of Prostatic Symptoms
Medical treatment for the symptoms of benign prostatic hyperplasia (BPH) consists of a blockers and 5-alpha-reductase inhibitors. Data suggest that 5-alpha-reductase inhibitors can prevent progression of BPH and reduce the risk of BPH-related surgery, especially in men with large-volume prostates. Results from the largest randomized, prospective, placebo-controlled trial, the Medical Therapy of Prostatic Symptoms trial, have been presented. These results support the notion of using 5-alpha-reductase inhibitors for the prevention of BPH progression and BPH-related surgery. Furthermore, long-term 5-alpha-reductase inhibitor monotherapy, although slow in onset, is a viable therapy for symptom relief in men with mild to moderate symptoms.
