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Publication Information
Affiliation
Department of Medicine (Renal Division), University of Alabama at Birmingham, Birmingham, Alabama, USA. arlene_chapman@emory.org
Authors
Bae KT, Baumgarten DA, Bennett WM, Brummer ME, Chapman AB, Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease cohort, Glockner JF, Grantham JJ, Guay-Woodford LM, Hirschman GH, Kenney PJ, Kimmel PL, King BF Jr, Klahr S, Miller JP, O'Neill WC, Robbin ML, Thompson PA, Torres VE, Wetzel LH
Studies
Citation
Chapman AB, Guay-Woodford LM, Grantham JJ, Torres VE, Bae KT, Baumgarten DA, Kenney PJ, King BF Jr, Glockner JF, Wetzel LH, Brummer ME, O'Neill WC, Robbin ML, Bennett WM, Klahr S, Hirschman GH, Kimmel PL, Thompson PA, Miller JP, Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease cohort. Renal structure in early autosomal-dominant polycystic kidney disease (ADPKD): The Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease (CRISP) cohort. Kidney Int 2003 Sep;64(3):1035-45.Abstract
Autosomal-dominant polycystic kidney disease (ADPKD) is characterized by gradual renal enlargement and cyst growth prior to loss of renal function. Standard radiographic imaging has not provided the resolution and accuracy necessary to detect small changes in renal volume or to reliably measure renal cyst volumes. The Consortium for Radiologic Imaging Studies in Polycystic Kidney Disease (CRISP) is longitudinally observing ADPKD individuals using high-resolution magnetic resonance (MR) imaging to determine if change in renal and cyst volumes can be detected over a short period of time, and if they correlate with decline in renal function early in disease.