PubMed ID:
12911554
Public Release Type:
Journal
Publication Year: 2003
Affiliation: Department of Medicine (Renal Division), University of Alabama at Birmingham, Birmingham, Alabama, USA. arlene_chapman@emory.org
DOI:
https://doi.org/10.1046/j.1523-1755.2003.00185.x
Authors:
Kimmel PL,
Torres VE,
Bae KT,
Baumgarten DA,
Bennett WM,
Brummer ME,
Chapman AB,
Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease cohort,
Glockner JF,
Grantham JJ,
Guay-Woodford LM,
Hirschman GH,
Kenney PJ,
King BF Jr,
Klahr S,
Miller JP,
O'Neill WC,
Robbin ML,
Thompson PA,
Wetzel LH
Studies:
Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease
Autosomal-dominant polycystic kidney disease (ADPKD) is characterized by gradual renal enlargement and cyst growth prior to loss of renal function. Standard radiographic imaging has not provided the resolution and accuracy necessary to detect small changes in renal volume or to reliably measure renal cyst volumes. The Consortium for Radiologic Imaging Studies in Polycystic Kidney Disease (CRISP) is longitudinally observing ADPKD individuals using high-resolution magnetic resonance (MR) imaging to determine if change in renal and cyst volumes can be detected over a short period of time, and if they correlate with decline in renal function early in disease.