PubMed ID:
12722030
Public Release Type:
Journal
Publication Year: 2003
Affiliation: Ohio State University, Nephrology, Columbus 43210, USA. hebert.1@osu.edu
DOI:
https://doi.org/10.1016/s0272-6386(03)00193-8
Authors:
Greene T,
Falkenhain ME,
Hebert LA,
Klahr S,
Levey A
Studies:
Modification of Diet in Renal Disease
Increased fluid intake slows renal disease progression in animal models. The relevance of these findings to human renal disease is not clear, although increased fluid intake often is recommended to patients with chronic renal insufficiency. This study tested the hypothesis that urine volume, urine osmolality (Uosm), or both are significantly associated with glomerular filtration rate (GFR) decline in patients with chronic renal insufficiency.