PubMed ID:
12472798
Public Release Type:
Journal
Publication Year: 2003
Affiliation: Department of Medicine, and Department of Statistics, University of California, Davis, California 95616, USA. gakaysen@ucdavis.edu
DOI:
https://doi.org/10.1046/j.1523-1755.2003.00721.x
Authors:
Dubin JA,
HEMO Group,
Kaysen GA,
Levin NW,
Mitch WE,
Müller HG,
Rosales L
Studies:
Hemodialysis Study
Fibrinogen is a risk factor for cardiovascular disease. It also is an acute phase protein (APP) and its plasma concentration increases with inflammation. Fibrinogen synthesis correlates with albumin synthesis in nephrotic patients and in patients with an expanded plasma volume even when serum albumin is normal and there is no inflammatory disease. The relationships among albumin synthesis, the acute phase response and plasma fibrinogen levels in hemodialysis patients are unknown.