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Publication Information

PubMed ID
Public Release Type
Journal
Publication Year
2018
Affiliation
Genetics and Genome Biology Program, Peter Gilgan Centre for Research and Learning (PGCRL), The Hospital for Sick Children, 686 Bay Street, Toronto, ON, M5G 1H3, Canada.; University Hospitals Case Western Medical Center, Cleveland, OH, USA.; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, ON, Canada.; Department of Mathematics and Statistics, McMaster University, Hamilton, ON, Canada.; Division of Nephrology and Hypertension, Diabetes and Metabolism Center, University of Utah, Salt Lake City, UT, USA.; Research Division, Joslin Diabetes Center, Boston, MA, USA.; Research Division, Joslin Diabetes Center, Boston, MA, USA.; Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI, USA.; Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI, USA.; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.; Institute for Biomedical and Clinical Science, University of Exeter Medical School, Exeter, UK.; Institute for Biomedical and Clinical Science, University of Exeter Medical School, Exeter, UK.; Genetics and Genome Biology Program, Peter Gilgan Centre for Research and Learning (PGCRL), The Hospital for Sick Children, 686 Bay Street, Toronto, ON, M5G 1H3, Canada. andrew.paterson@sickkids.ca.
Authors
Roshandel Delnaz, Gubitosi-Klug Rose, Bull Shelley B, Canty Angelo J, Pezzolesi Marcus G, King George L, Keenan Hillary A, Snell-Bergeon Janet K, Maahs David M, Klein Ronald, Klein Barbara E K, Orchard Trevor J, Costacou Tina, Weedon Michael N, Oram Richard A, Paterson Andrew D
Studies

Abstract

The aim of this study was to identify genetic variants associated with beta cell function in type 1 diabetes, as measured by serum C-peptide levels, through meta-genome-wide association studies (meta-GWAS).