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Publication Information
Affiliation
Department of Family Medicine and Public Health, University of California San Diego, La Jolla, California.; Division of Endocrinology, Department of Pediatrics, Boston Children's Hospital, Boston, Massachusetts.; Folkhälsan Research Center, Folkhälsan Institute of Genetics, Helsinki, Finland.; Division of Endocrinology, Department of Pediatrics, Boston Children's Hospital, Boston, Massachusetts.; Center for Public Health Genomics, School of Medicine, University of Virginia, Charlottesville, Virginia.; Diabetes Complications Research Centre, Conway Institute, School of Medicine and Medical Sciences, University College Dublin, Dublin, Ireland.; Division of Nephrology and Hypertension, Diabetes and Metabolism Center, University of Utah, Salt Lake City, Utah.; Usher Institute of Population Health Sciences and Informatics and.; The Hospital for Sick Children, Toronto, Ontario, Canada.; Departments of Medicine and Genetics, University of Pennsylvania, Philadelphia, Pennsylvania.; Division of Nephrology, Department of Internal Medicine and.; The Hospital for Sick Children, Toronto, Ontario, Canada.; The Hospital for Sick Children, Toronto, Ontario, Canada.; Folkhälsan Research Center, Folkhälsan Institute of Genetics, Helsinki, Finland.; Center for Public Health Genomics, School of Medicine, University of Virginia, Charlottesville, Virginia.; Joslin Diabetes Center, Boston, Massachusetts.; Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.; Folkhälsan Research Center, Folkhälsan Institute of Genetics, Helsinki, Finland.; Folkhälsan Research Center, Folkhälsan Institute of Genetics, Helsinki, Finland.; Diabetes Complications Research Centre, Conway Institute, School of Medicine and Medical Sciences, University College Dublin, Dublin, Ireland.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Genomics, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden.; Diabetes Complications Research Centre, Conway Institute, School of Medicine and Medical Sciences, University College Dublin, Dublin, Ireland.; Steno Diabetes Center Copenhagen, Gentofte, Denmark.; Steno Diabetes Center Copenhagen, Gentofte, Denmark.; Diabetes Complications Research Centre, Conway Institute, School of Medicine and Medical Sciences, University College Dublin, Dublin, Ireland.; Departments of Medicine and Genetics, University of Pennsylvania, Philadelphia, Pennsylvania.; Joslin Diabetes Center, Boston, Massachusetts.; Usher Institute of Population Health Sciences and Informatics and.; Department of Biostatistics and.; Division of Nephrology, Department of Internal Medicine and.; Cardiometabolic Diseases Research, Boehringer Ingelheim, Ridgefield, Connecticut.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan.; Chronic Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona.; University of Wisconsin-Madison, Madison, Wisconsin.; University of Wisconsin-Madison, Madison, Wisconsin.; University of Wisconsin-Madison, Madison, Wisconsin.; The George Washington University, Washington, DC.; University of Minnesota, Minneapolis, Minnesota.; Complications of Diabetes Unit, Division of Immunology, Transplantation and Infectious Diseases, Diabetes Research Institute, IRCCS San Raffaele Scientific Institute, Milano, Italy.; University of Minnesota, Minneapolis, Minnesota.; University of Washington, Seattle, Washington.; University of Pittsburgh Public Health, Pittsburgh, Pennsylvania.; University of Pittsburgh Public Health, Pittsburgh, Pennsylvania.; The Hospital for Sick Children, Toronto, Ontario, Canada.; INSERM UMR_S 1166, Sorbonne Université, UPMC Univ Paris 06, Paris, France.; INSERM UMR_S 1166, Sorbonne Université, UPMC Univ Paris 06, Paris, France.; University of Colorado School of Medicine, Aurora, Colorado.; Department of Pediatrics-Endocrinology, Stanford University, Stanford, California.; The Lunenfeld-Tanenbaum Research Institute, University of Toronto, Toronto, Ontario, Canada.; Department of Mathematics and Statistics, McMaster University, Hamilton, Ontario, Canada.; Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.; First Department of Medicine, Paracelsus Medical University, Salzburg, Austria.; First Department of Medicine, Paracelsus Medical University, Salzburg, Austria.; First Department of Medicine, Paracelsus Medical University, Salzburg, Austria.; University of Latvia, Riga, Latvia.; Latvian Biomedical Research and Study Centre, Riga, Latvia.; University of Latvia, Riga, Latvia.; Medical Academy and.; Institute of Endocrinology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.; Institute of Endocrinology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.; Abdominal Center Nephrology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Department of Genomics, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Clinical Science, Intervention and Technology and.; Division of Pediatrics, Department of Clinical Sciences, Umeå University, Umeå, Sweden.; Department of Molecular Medicine and Surgery, Rolf Luft Center for Diabetes Research and Endocrinology, Karolinska Institutet, Stockholm, Sweden.; Department of Molecular Medicine and Surgery, Rolf Luft Center for Diabetes Research and Endocrinology, Karolinska Institutet, Stockholm, Sweden.; Diabetes Complications Research Centre, Conway Institute, School of Medicine and Medical Sciences, University College Dublin, Dublin, Ireland.; Steno Diabetes Center Copenhagen, Gentofte, Denmark.; University of Pittsburgh Public Health, Pittsburgh, Pennsylvania.; Complications of Diabetes Unit, Division of Immunology, Transplantation and Infectious Diseases, Diabetes Research Institute, IRCCS San Raffaele Scientific Institute, Milano, Italy.; Department of Diabetology, Endocrinology and Nutrition, Bichat Hospital, DHU FIRE, Assistance Publique-Hôpitaux de Paris, Paris, France.; Department of Endocrinology and Diabetology, Centre Hospitalier Universitaire de Poitiers, Poitiers, France.; Centre for Public Health, Queens University of Belfast, Northern Ireland, UK.; Folkhälsan Research Center, Folkhälsan Institute of Genetics, Helsinki, Finland.; Centre for Public Health, Queens University of Belfast, Northern Ireland, UK.; Diabetes Complications Research Centre, Conway Institute, School of Medicine and Medical Sciences, University College Dublin, Dublin, Ireland.; Centre for Public Health, Queens University of Belfast, Northern Ireland, UK.; Division of Nephrology, Department of Internal Medicine and.; Departments of Medicine and Genetics, University of Pennsylvania, Philadelphia, Pennsylvania.; Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.; Joslin Diabetes Center, Boston, Massachusetts.; The Hospital for Sick Children, Toronto, Ontario, Canada.; Folkhälsan Research Center, Folkhälsan Institute of Genetics, Helsinki, Finland.; Center for Public Health Genomics, School of Medicine, University of Virginia, Charlottesville, Virginia.; Division of Endocrinology, Department of Pediatrics, Boston Children's Hospital, Boston, Massachusetts.; Programs in Metabolism and Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts; jcflorez@mgh.harvard.edu.
Authors
Salem Rany M, Todd Jennifer N, Sandholm Niina, Cole Joanne B, Chen Wei-Min, Andrews Darrell, Pezzolesi Marcus G, McKeigue Paul M, Hiraki Linda T, Qiu Chengxiang, Nair Viji, Di Liao Chen, Cao Jing Jing, Valo Erkka, Onengut-Gumuscu Suna, Smiles Adam M, McGurnaghan Stuart J, Haukka Jani K, Harjutsalo Valma, Brennan Eoin P, van Zuydam Natalie, Ahlqvist Emma, Doyle Ross, Ahluwalia Tarunveer S, Lajer Maria, Hughes Maria F, Park Jihwan, Skupien Jan, Spiliopoulou Athina, Liu Andrew, Menon Rajasree, Boustany-Kari Carine M, Kang Hyun M, Nelson Robert G, Klein Ronald, Klein Barbara E, Lee Kristine E, Gao Xiaoyu, Mauer Michael, Maestroni Silvia, Caramori Maria Luiza, de Boer Ian H, Miller Rachel G, Guo Jingchuan, Boright Andrew P, Tregouet David, Gyorgy Beata, Snell-Bergeon Janet K, Maahs David M, Bull Shelley B, Canty Angelo J, Palmer Colin N A, Stechemesser Lars, Paulweber Bernhard, Weitgasser Raimund, Sokolovska Jelizaveta, Rovīte Vita, Pīrāgs Valdis, Prakapiene Edita, Radzeviciene Lina, Verkauskiene Rasa, Panduru Nicolae Mircea, Groop Leif C, McCarthy Mark I, Gu Harvest F, Möllsten Anna, Falhammar Henrik, Brismar Kerstin, Martin Finian, Rossing Peter, Costacou Tina, Zerbini Gianpaolo, Marre Michel, Hadjadj Samy, McKnight Amy J, Forsblom Carol, McKay Gareth, Godson Catherine, Maxwell A Peter, Kretzler Matthias, Susztak Katalin, Colhoun Helen M, Krolewski Andrzej, Paterson Andrew D, Groop Per-Henrik, Rich Stephen S, Hirschhorn Joel N, Florez Jose C
Studies
Abstract
Although diabetic kidney disease demonstrates both familial clustering and single nucleotide polymorphism heritability, the specific genetic factors influencing risk remain largely unknown.