An official website of the United States government

This repository is under review for potential modification in compliance with Administration directives.

Publication Information

PubMed ID
Public Release Type
Journal
Publication Year
2021
Affiliation
Population Health Sciences Program, Harvard University, Boston, MA, USA.; Department of Epidemiology and Biostatistics, Biostatistics Center and Milken Institute School of Public Health, George Washington University, Rockville, MD, USA.; Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Pediatric Endocrinology and Diabetes, Maine Medical Center and Center for Outcomes Research and Evaluation, Maine Medical Center Research Institute, Portland, ME, USA.; Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA, USA; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA.; National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, AZ, USA.; New York Obesity Research Center, Division of Endocrinology, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.; Department of Epidemiology, Lifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, Colorado School of Public Health, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, USA.; Pennington Biomedical Research Center/Louisiana State University, Baton Rouge, LA, USA.; Division of Endocrinology, Metabolism, and Molecular Medicine, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Division of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA; Diabetes Unit, Massachusetts General Hospital, Boston, MA, USA.; Division of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA.; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Harvard T.H. Chan School of Public Health and Division of women's Health, Department of Medicine, Connors Center for women's Health and Gender Biology, Brigham and women's Hospital and Harvard Medical School, Boston, MA, USA.; Department of Epidemiology and Biostatistics, Biostatistics Center and Milken Institute School of Public Health, George Washington University, Rockville, MD, USA. Electronic address: dppmail@bsc.gwu.edu.
Authors
Mitro Susanna D., Liu Jinxi, Jaacks Lindsay M., Fleisch Abby F., Williams Paige L., Knowler William C., Laferrère Blandine, Perng Wei, Bray George A., Wallia Amisha, Hivert Marie-France, Oken Emily, James-Todd Tamarra M., Temprosa Marinella
Studies

Abstract

Per- and polyfluoroalkyl substances (PFAS) are widely used chemicals, some of which have been linked to type 2 diabetes. We tested whether PFAS concentrations were cross-sectionally associated with metabolites previously shown to predict incident type 2 diabetes using the Diabetes Prevention Program (DPP), a trial of individuals at high risk of type 2 diabetes.