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Publication Information
Authors
Li Dalin, Achkar Jean-Paul, Haritunians Talin, Jacobs Jonathan P, Hui Ken Y, D’Amato Mauro, Brand Stephan, Radford-Smith Graham, Halfvarson Jonas, Niess Jan-Hendrik, Kugathasan Subra, Büning Carsten, Schumm L Philip, Klei Lambertus, Ananthakrishnan Ashwin, Aumais Guy, Baidoo Leonard, Dubinsky Marla, Fiocchi Claudio, Glas Jürgen, Milgrom Raquel, Proctor Deborah D, Regueiro Miguel, Simms Lisa A, Stempak Joanne M, Targan Stephan R., Törkvist Leif, Sharma Yashoda, Devlin Bernie, Borneman James, Hakonarson Hakon, Xavier Ramnik J, Daly Mark, Brant Steven R, Rioux John D, Silverberg Mark S, Cho Judy H, Braun Jonathan, McGovern Dermot PB, Duerr Richard H
Studies
Abstract
Genome-wide association studies (GWAS) have identified 200 inflammatory bowel disease (IBD) loci, but the genetic architecture of Crohn’s disease (CD) and ulcerative colitis (UC) remains incompletely defined. Here we aimed to identify novel associations between IBD and functional genetic variants using the Illumina ExomeChip.