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Publication Information
Affiliation
Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, 27599, USA; AdventHealth Translational Research Institute, Orlando, 32804, USA. Electronic address: daria.igudesman@adventhealth.com.; Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, 27599, USA.; AdventHealth Translational Research Institute, Orlando, 32804, USA.; Department of Pediatrics, Division of Endocrinology, Stanford University, Stanford, 94304, USA.; Department of Pediatrics, Division of Endocrinology, Stanford University, Stanford, 94304, USA.; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, 27599, USA.; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, 27599, USA; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, USA; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, 27599, USA.; AdventHealth Translational Research Institute, Orlando, 32804, USA.; Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, 27599, USA.; Department of Pediatrics, Division of Endocrinology, Stanford University, Stanford, 94304, USA.; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, 27599, USA.; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, 27599, USA; Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, 27599, USA.
Authors
Igudesman Daria, Crandell Jamie, Corbin Karen D, Zaharieva Dessi P, Addala Ananta, Thomas Joan M, Bulik Cynthia M, Pence Brian W, Pratley Richard E, Kosorok Michael R, Maahs David M, Carroll Ian M, Mayer-Davis Elizabeth J
Studies
Abstract
Disordered eating (DE) in type 1 diabetes (T1D) includes insulin restriction for weight loss with serious complications. Gut microbiota-derived short chain fatty acids (SCFA) may benefit host metabolism but are reduced in T1D. We evaluated the hypothesis that DE and insulin restriction were associated with reduced SCFA-producing gut microbes, SCFA, and intestinal microbial diversity in adults with T1D.