An official website of the United States government
This repository is under review for potential modification in compliance with Administration directives.
Publication Information
Affiliation
Sheba Medical Center, Tel-Hashomer, affiliated with the Tel Aviv University; Sheba Medical Center, Tel-Hashomer, affiliated with the Tel Aviv University; Sheba Medical Center, Tel-Hashomer, affiliated with the Tel Aviv University; Sheba Medical Center, Tel-Hashomer, affiliated with the Tel Aviv University; Sheba Medical Center, Tel-Hashomer, affiliated with the Tel Aviv University; Cincinnati Children’s Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine; Sheba Medical Center, Tel-Hashomer, affiliated with the Tel Aviv University; Sheba Medical Center, Tel-Hashomer, affiliated with the Tel Aviv University; Sheba Medical Center, Tel-Hashomer, affiliated with the Tel Aviv University; Sheba Medical Center, Tel-Hashomer, affiliated with the Tel Aviv University; Department of Pediatrics and Child Health, Aga Khan University; Department of Pediatrics, University of Virginia; Emory University; The Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology; Sheba Medical Center, Tel-Hashomer, affiliated with the Tel Aviv University; Sheba Medical Center, Tel-Hashomer, affiliated with the Tel Aviv University; Sheba Medical Center, Tel-Hashomer, affiliated with the Tel Aviv University; The Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology; Department of Molecular Cell Biology, Weizmann Institute of Science; Sheba Medical Center, Tel-Hashomer, affiliated with the Tel Aviv University; Departments of Biological Regulation and Molecular Neuroscience, Weizmann Institute of Science; Connecticut Children’s Medical Center; Cincinnati Children’s Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine; Sheba Medical Center, Tel-Hashomer, affiliated with the Tel Aviv University
Authors
Sosnovski Katya E, Braun Tzipi, Amir Amnon, Moshel Danielle, BenShoshan Marina, VanDussen Kelli L, Levhar Nina, Abbas-Egbariya Haya, Beider Katia, Ben-Yishay Rakefet, Asad Ali Syed, Moore Sean R, Kugathasan Subra, Abramovich Ifat, Glick Saar Efrat, Weiss Batya, Barshack Iris, Gottlieb Eyal, Geiger Tamar, Ben-Horin Shomron, Ulitsky Igor, Hyams Jeffrey S, Denson Lee A, Haberman Yael
Studies
Abstract
Widespread dysregulation of long non-coding RNAs [lncRNAs] including a reduction in GATA6-AS1 was noted in inflammatory bowel disease [IBD]. We previously reported a prominent inhibition of epithelial mitochondrial functions in ulcerative colitis [UC]. However, the connection between reduction of GATA6-AS1 expression and attenuated epithelial mitochondrial functions was not defined.