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HALT PKD

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Title
PMID
PMCID
Public Release Type
Publication Year
DOI
Study Acronym
Study Network
Request ID(s)
Public Release Origin
A meta-analysis of GFR slope as a surrogate endpoint for kidney failure37330614Journal202310.1038/s41591-023-02418-0FSGS/FONT, FONT II, HALT PKDFSGS Study Group (FSGS), The HALT Progression of Polycystic Kidney Disease (HALT PKD Network)22864, 23584Secondary Research
ADPKD Progression in Patients With No Apparent Family History and No Mutation Detected by Sanger Sequencing29203126PMC6267804Journal201810.1053/j.ajkd.2017.09.008HALT PKDThe HALT Progression of Polycystic Kidney Disease (HALT PKD Network)20790Secondary Research
Acute treatment effects on GFR in randomized clinical trials of kidney disease progression.34862238PMC8819983Journal202210.1681/ASN.2021070948HALT PKDThe HALT Progression of Polycystic Kidney Disease (HALT PKD Network)21181Secondary Research
Baseline total kidney volume and the rate of kidney growth are associated with chronic kidney disease progression in Autosomal Dominant Polycystic Kidney Disease29290310PMC5826779Journal201710.1016/j.kint.2017.09.027HALT PKDThe HALT Progression of Polycystic Kidney Disease (HALT PKD Network)20790Secondary Research
CD8+ T cells modulate autosomal dominant polycystic kidney disease progression30249452PMC6319903Journal201810.1016/j.kint.2018.06.025HALT PKDThe HALT Progression of Polycystic Kidney Disease (HALT PKD Network)20959Secondary Research
Change in albuminuria and GFR slope as joint surrogate endpoints for kidney failure - Implications for phase 2 clinical trials in chronic kidney disease36918388Journal202310.1681/ASN.0000000000000117HALT PKDThe HALT Progression of Polycystic Kidney Disease (HALT PKD Network)21181Secondary Research
Collagen IV Gene Mutations in Adults With Bilateral Renal Cysts and CKD31922066PMC6943786Journal201910.1016/j.ekir.2019.09.004HALT PKDThe HALT Progression of Polycystic Kidney Disease (HALT PKD Network)21532, 21588, 21748Secondary Research
Detection and characterization of mosaicism in autosomal dominant polycystic kidney disease.31874800PMC7218796Journal202010.1016/j.kint.2019.08.038HALT PKDThe HALT Progression of Polycystic Kidney Disease (HALT PKD Network)20790, 20959, 21225, 21507, 22080Secondary Research
Development of a Clinical Trial Enrichment (CTE) Tool for Autosomal Dominant Polycystic Kidney DiseaseConference Presentation2023CRISP, HALT PKDConsortium for Radiologic Imaging Studies of Polycystic Kidney Disease (CRISP Network), The HALT Progression of Polycystic Kidney Disease (HALT PKD Network)22905Secondary Research
Effects of Tolvaptan on Kidney Function Decline in Patients Aged >55 Years With Autosomal Dominant Polycystic Kidney Disease: Pooled Data Analysis37250503PMC10220412Journal202310.1016/j.xkme.2023.100639CRISP, HALT PKDConsortium for Radiologic Imaging Studies of Polycystic Kidney Disease (CRISP Network), The HALT Progression of Polycystic Kidney Disease (HALT PKD Network)21540Secondary Research
Ganetespib limits ciliation and cystogenesis in autosomal-dominant polycystic kidney disease (ADPKD)29401581PMC5901382Journal201810.1096/fj.201700909RHALT PKDThe HALT Progression of Polycystic Kidney Disease (HALT PKD Network)21532, 21588Secondary Research
Impact of early glomerular filtration rate decline in response to antihypertensive treatment on risk of end-stage kidney disease and cardiovascular outcomes: a systematic review and meta-analysis34930868Journal202210.1097/HJH.0000000000003066HALT PKDThe HALT Progression of Polycystic Kidney Disease (HALT PKD Network)23180Secondary Research
Interactions between FGF23 and Genotype in Autosomal Dominant Polycystic Kidney Disease.33305291PMC7725226Journal202010.34067/KID.0001692020HALT PKDThe HALT Progression of Polycystic Kidney Disease (HALT PKD Network)20790, 20959Secondary Research
KIDNEY FUNCTION DECLINE IN AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE PATIENTS: ASSESSMENT OF TOLVAPTAN'S REAL WORLD EFFECTIVENESSConference Presentation2023CRISP, HALT PKDConsortium for Radiologic Imaging Studies of Polycystic Kidney Disease (CRISP Network), The HALT Progression of Polycystic Kidney Disease (HALT PKD Network)21540Secondary Research
KIM-1 and Kidney Disease Progression in Autosomal Dominant Polycystic Kidney Disease: HALT-PKD Results.32541154PMC7384479Journal202010.1159/000508051HALT PKDThe HALT Progression of Polycystic Kidney Disease (HALT PKD Network)20959, 22080Secondary Research
Long-term trajectory of kidney function in autosomal-dominant polycystic kidney disease.30922668PMC6478515Journal201910.1016/j.kint.2018.12.023HALT PKDThe HALT Progression of Polycystic Kidney Disease (HALT PKD Network)20790Secondary Research
Longitudinal Assessment of Left Ventricular Mass in Autosomal Dominant Polycystic Kidney Disease.29854969PMC5976807Journal201810.1016/j.ekir.2017.12.011HALT PKDThe HALT Progression of Polycystic Kidney Disease (HALT PKD Network)20790Secondary Research
Monoallelic IFT140 pathogenic variants are an important cause of the autosomal dominant polycystic kidney-spectrum phenotype.34890546PMC8764120Journal202210.1016/j.ajhg.2021.11.016HALT PKDThe HALT Progression of Polycystic Kidney Disease (HALT PKD Network)21225Secondary Research
Mutations in GANAB, Encoding the Glucosidase IIα Subunit, Cause Autosomal-Dominant Polycystic Kidney and Liver Disease.27259053PMC4908191Journal201610.1016/j.ajhg.2016.05.004HALT PKDThe HALT Progression of Polycystic Kidney Disease (HALT PKD Network)20790, 21225Secondary Research
Overweight and Obesity Are Predictors of Progression in Early Autosomal Dominant Polycystic Kidney Disease.29118087PMC5791072Journal201810.1681/ASN.2017070819HALT PKDThe HALT Progression of Polycystic Kidney Disease (HALT PKD Network)20790, 20959Secondary Research
Overweight and Obesity and Progression of ADPKD34117082PMC8216617Journal202110.2215/CJN.16871020HALT PKDThe HALT Progression of Polycystic Kidney Disease (HALT PKD Network)20959, 22080Secondary Research
POOLED DATA ANALYSIS OF THE EFFECT OF TOLVAPTAN IN PATIENTS AGED 18-35 YEARS WITH AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE35570988PMC9091612Conference Presentation202310.1016/j.ekir.2022.02.009CRISP, HALT PKDConsortium for Radiologic Imaging Studies of Polycystic Kidney Disease (CRISP Network), The HALT Progression of Polycystic Kidney Disease (HALT PKD Network)21540Secondary Research
Pain and Obesity in Autosomal Dominant Polycystic Kidney Disease: A Post Hoc Analysis of the Halt Progression of Polycystic Kidney Disease (HALT-PKD) Studies.34401721PMC8350824Journal202110.1016/j.xkme.2021.03.004HALT PKDThe HALT Progression of Polycystic Kidney Disease (HALT PKD Network)20790, 20959, 22080Secondary Research
Plasma metabolites and lipids associate with kidney function and kidney volume in hypertensive ADPKD patients early in the disease course.30803434PMC6388487Journal201910.1186/s12882-019-1249-6HALT PKDThe HALT Progression of Polycystic Kidney Disease (HALT PKD Network)20790, 21328Secondary Research
Predicted Mutation Strength of Nontruncating PKD1 Mutations Aids Genotype-Phenotype Correlations in Autosomal Dominant Polycystic Kidney Disease.26823553PMC5004648Journal201610.1681/ASN.2015050583HALT PKDThe HALT Progression of Polycystic Kidney Disease (HALT PKD Network)20790Secondary Research
The STAGED-PKD 2-Stage Adaptive Study With a Patient Enrichment Strategy and Treatment Effect Modeling for Improved Study Design Efficiency in Patients With ADPKD.36204243PMC9529969Journal202210.1016/j.xkme.2022.100538HALT PKDThe HALT Progression of Polycystic Kidney Disease (HALT PKD Network)20790, 20997Secondary Research
The Value of Genetic Testing in Polycystic Kidney Diseases Illustrated by a Family With PKD2 and COL4A1 Mutations.29395486PMC6057824Journal201810.1053/j.ajkd.2017.11.015HALT PKDThe HALT Progression of Polycystic Kidney Disease (HALT PKD Network)21225, 21507Secondary Research
The tryptophan-metabolizing enzyme indoleamine 2,3-dioxygenase 1 regulates polycystic kidney disease progression36422996PMC9870090Journal202310.1172/jci.insight.154773HALT PKDThe HALT Progression of Polycystic Kidney Disease (HALT PKD Network)20959, 22080Secondary Research
The value of genotypic and imaging information to predict functional and structural outcomes in ADPKD.32634120PMC7455088Journal202010.1172/jci.insight.138724HALT PKDThe HALT Progression of Polycystic Kidney Disease (HALT PKD Network)20790Secondary Research
Tolvaptan and Kidney Function Decline in Older Individuals With Autosomal Dominant Polycystic Kidney Disease: A Pooled Analysis of Randomized Clinical Trials and Observational Studies.37250503PMC10220412Journal202310.1016/j.xkme.2023.100639HALT PKDThe HALT Progression of Polycystic Kidney Disease (HALT PKD Network)21540Secondary Research
Vascular Dysfunction, Oxidative Stress, and Inflammation in Autosomal Dominant Polycystic Kidney Disease30228110PMC6218833Journal201810.2215/CJN.05850518HALT PKDThe HALT Progression of Polycystic Kidney Disease (HALT PKD Network)20959Secondary Research
Volume Progression and Imaging Classification of Polycystic Liver in Early Autosomal Dominant Polycystic Kidney Disease.35217526PMC8975034Journal202210.2215/CJN.08660621HALT PKDThe HALT Progression of Polycystic Kidney Disease (HALT PKD Network)20790Secondary Research
Weight loss and cystic disease progression in autosomal dominant polycystic kidney disease35059607PMC8760407Journal202110.1016/j.isci.2021.103697HALT PKDThe HALT Progression of Polycystic Kidney Disease (HALT PKD Network)20959, 22080Secondary Research
An update on the use of tolvaptan for autosomal dominant polycystic kidney disease: consensus statement on behalf of the ERA Working Group on Inherited Kidney Disorders, the European Rare Kidney Disease Reference Network and Polycystic Kidney Disease International35134221PMC9035348Journal202210.1093/ndt/gfab312HALT PKDThe HALT Progression of Polycystic Kidney Disease (HALT PKD Network)21225Secondary Research
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