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Number of Subjects in Study Archive: 160 families with IC, 61 mother-daughter pairs, 122 other families
Study Design: Observational
Conditions: Cystitis, Interstitial, Urogenital Diseases
Division: KUH
Duration: June 2004 – November 2008
# Recruitment Centers: 1
Treatment: None, observational only
Available Genotype Data: No
Image Summary: No
Transplant Type: None
Does it have dialysis patients: No
Clinical Trials URL:
http://www.clinicaltrials.gov/show/NCT00237081
Data Package Version Number: 3 (Updated on: November 6, 2015)
DOI: 10.58020/akda-0m02
How to cite this dataset: Warren, J (2023). Maryland Genetics of Interstitial Cystitis Study (V3) [Dataset]. NIDDK Central Repository. https://doi.org/10.58020/akda-0m02
Data availability statement: Data from the Maryland Genetics of Interstitial Cystitis Study [(V3)/https://doi.org/10.58020/akda-0m02] reported here are available for request at the NIDDK Central Repository (NIDDK-CR) website, Resources for Research (R4R), https://repository.niddk.nih.gov/.
The Maryland Genetics of Interstitial Cystitis Study (MaGIC) collected information on several hundred families with two or more blood relatives with interstitial cystitis (IC) to investigate the genetic basis of the condition. The study sought to find genetic variants that are more prevalent in family members who have interstitial cystitis than in those who do not have the disease. Participants who had IC and at least one blood relative with the condition were enrolled. Information was collected via interview by phone, mail, or website.
The primary objective of the study was to identify genetic variants associated with IC, with the aim using the genetic information to advance understanding of the cause of the disease.
The study enrolled participants of 13 years of age or older who had IC or PBS; had at least one relative with IC, PBS, or similar urinary symptoms; were available for an interview by phone, mail, or website; and lived in the US or Canada.
Subjects meeting the above criteria who had Parkinson’s disease, Multiple Sclerosis, Spina bifida, or another neurologic disease that preceded interstitial cystitis symptoms were excluded.
Pedigree files based on tracking of IC and related conditions were generated.
Specimens and Study Datasets
| Urine | 4849 |
| DNA | 842 |
| documentation | ||
| forms |
 |
Data Dictionary (PDF) - 173.0 KB | |
| |
Roadmap (PDF) - 23.3 KB | |
| |
ST-VRG Revised (PDF) - 35.9 KB |
If you need accessible versions of documents, please email your request to NIDDK-CRsupport@niddk.nih.gov.
