The Modification of Diet in Renal Disease (MDRD) study consisted of two randomized clinical trials that investigated whether protein restriction and control of blood pressure had an effect on the progression of chronic kidney disease (CKD). The study tested two hypotheses—that (1) a reduction in dietary protein and phosphorous intake and (2) the maintenance of blood pressure at a level below that usually recommended safely and effectively delays the progression of CKD.
In study 1, 585 patients with glomerular filtration rates (GFR) of 25-55 ml/min/1.73 m2 of body-surface area were randomly assigned to a usual-protein diet or a low-protein diet (1.3 or 0.58 g of protein per kilogram of body weight per day) and to a usual- or a low-blood-pressure group (mean arterial pressure, 107 or 92 mm Hg). In study 2, 255 patients with GFR of 13 to 24 ml/min/1.73 m2 were randomly assigned to the low-protein diet (0.58 g per kilogram per day) or a very-low-protein diet (0.28 g per kilogram per day) with a keto acid-amino acid supplement, and a usual- or a low-blood-pressure group (same values as those in study 1). The length of follow-up varied from 18-to-45-months, with monthly evaluations of the patients. The primary outcome was the change in GFR rate over time. The study found that among patients with moderate renal insufficiency, the slower decline in renal function that started four months after the introduction of a low-protein diet suggests a small benefit of this dietary intervention. Among patients with more severe renal insufficiency, a very-low-protein diet, as compared with a low-protein diet, did not significantly slow the progression of renal disease.
The MDRD study aimed to investigate the effect of protein restriction and blood pressure control on the progression of disease in patients with chronic renal diseases. The study hypothesized that a reduction in dietary protein and phosphorous intake and the maintenance of blood pressure below recommended levels would delay the progression of renal disease.
The primary outcome measure used to assess renal function was the rate of change in glomerular filtration rate over time.
The following enrollment criteria were used:
Glomerular filtration rate (GFR) was used to separate patients into study 1 or study 2. During a three-month base-line period, patients were deemed eligible for study 1 if their GFR was 25-55 ml/min/1.73 m2, and their dietary protein intake was ≥ 0.9 g/kg of body weight per day. Patients were eligible for study 2 if their GFR was 13-24 ml/min/1.73 m2, irrespective of protein intake.
Exclusion criteria are documented in the protocol
Among patients with moderate renal insufficiency, the slower decline in renal function that started four months after the introduction of a low-protein diet suggests a small benefit of this dietary intervention. Among patients with more severe renal insufficiency, a very-low-protein diet, as compared with a low-protein diet, did not significantly slow the progression of renal disease. Overall, a low blood pressure goal was not shown to have benefit over the higher goal. Among persons with more pronounced proteinuria at baseline had a significantly slower rate of decline in GFR
Nutrition, Multidisciplinary Research, Kidney Disease
Interventional
15
1988-10
2016-01
Chronic Kidney Disease
Low-Protein Diet, Blood Pressure, Protien Restriction, Disease Progression, Glomerular Filtration Rate (GFR), Randomized Clinical Trial, Phosphorous Intake, Chronic Renal Insufficiency
Division of Kidney, Urologic, and Hematologic Diseases
Document Name | Description | Document Type | File Format |
---|---|---|---|
Form 28 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 28 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 29 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 29 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Analysis Datasets SAS Formats | SAS Formats file that provides the values and value labels for the variables in MDRD Analysis datasets | Formats/Dataset Instruction | TXT |
Form 01 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 01 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 01 (Screened) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 01 (Screened) Dataset | Formats/Dataset Instruction | SAS |
Form 02 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 02 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 02 (Screened) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 02 (Screened) Dataset | Formats/Dataset Instruction | SAS |
Form 03 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 03 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 03 (Screened) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 03 (Screened) Dataset | Formats/Dataset Instruction | SAS |
Form 04 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 04 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 05 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 05 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 06 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 06 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 07 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 07 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 07 (Screened) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 07 (Screened) Dataset | Formats/Dataset Instruction | SAS |
Form 08 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 08 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 09 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 09 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 10 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 10 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 11 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 11 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 12 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 12 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 13 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 13 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 14 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 14 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 15 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 15 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 15 (Screened) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 15 (Screened) Dataset | Formats/Dataset Instruction | SAS |
Form 16 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 16 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 17 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 17 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 18 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 18 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 19 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 19 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 20 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 20 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 21 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 21 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 22 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 22 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 23 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 23 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 24 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 24 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 24 (Screened) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 24 (Screened) Dataset | Formats/Dataset Instruction | SAS |
Form 25 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 25 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 25 (Screened) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 25 (Screened) Dataset | Formats/Dataset Instruction | SAS |
Form 26 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 26 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 27 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 27 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 29 (Screened) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 29 (Screened) Dataset | Formats/Dataset Instruction | SAS |
Form 30 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 30 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 31 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 31 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 32 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 32 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 33 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 33 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 34 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 34 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 35 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 35 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 36 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 36 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 37 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 37 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 38 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 38 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 39 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 39 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 40 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 40 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 41 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 41 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 41 (Screened) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 41 (Screened) Dataset | Formats/Dataset Instruction | SAS |
Form 42 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 42 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 43 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 43 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 44 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 44 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 45 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 45 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 46 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 46 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 46 (Screened) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 46 (Screened) Dataset | Formats/Dataset Instruction | SAS |
Form 47 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 47 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 48 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 48 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 49 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 49 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 50 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 50 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 50 (Screened) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 50 (Screened) Dataset | Formats/Dataset Instruction | SAS |
Form 51 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 51 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 51 (Screened) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 51 (Screened) Dataset | Formats/Dataset Instruction | SAS |
Form 52 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 52 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 53 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 53 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 54 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 54 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 55 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 55 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 56 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 56 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 62 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 62 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 64 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 64 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 65 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 65 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 66 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 66 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 70 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 70 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 71 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 71 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 72 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 72 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 73 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 73 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 74 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 74 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 76 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 76 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 77 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 77 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 77 (Screened) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 77 (Screened) Dataset | Formats/Dataset Instruction | SAS |
Form 78 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 78 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 78 (Screened) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 78 (Screened) Dataset | Formats/Dataset Instruction | SAS |
Form 79 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 79 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 80 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 80 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 81 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 81 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 90 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 90 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 91 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 91 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 92 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 92 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 93 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 93 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 94 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 94 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 95 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 95 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 96 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 96 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 97 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 97 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 98 (Enrolled) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 98 (Enrolled) Dataset | Formats/Dataset Instruction | SAS |
Form 98 (Screened) Dataset SAS Formats | SAS Formats file that provides the values and value labels for the variables in the Form 98 (Screened) Dataset | Formats/Dataset Instruction | SAS |
Dataset Name | Description | # of Records | # of Variables | File Format(s) |
---|---|---|---|---|
Form 81 (Enrolled) Dataset | Contains data obtained from Form 81 - Low Protein Entree (Includes data on enrolled participants only) | 402 | csv (38.23 KB) | |
Form 79 (Enrolled) Dataset | Contains data obtained from Form 79 - Nutrition History Questions (Includes data on enrolled participants only) | 11676 | csv (1.4 MB) | |
Form 27 (Enrolled) Dataset | Contains data obtained from Form 27 - Economic Information (Includes data on enrolled participants only) | 5440 | csv (1.01 MB) | |
Form 04 (Enrolled) Dataset | Contains data obtained from Form 04 - Demographic & Baseline Exam (Includes data on enrolled participants only) | 1935 | csv (725.92 KB) | |
Form 56 (Enrolled) Dataset | Contains data obtained from Form 56 - Food Record Form (Includes data on enrolled participants only) | 2291 | csv (237.1 KB) | |
Form 52 (Enrolled) Dataset | Contains data obtained from Form 52 - Dialysis Delivery Draft Form (Includes data on enrolled participants only) | 6370 | csv (624.43 KB) | |
Form 01 (Screened) Dataset | Contains data obtained from Form 01 - Chart Screening (Includes data on all screened individuals) | 4443 | csv (417.2 KB) | |
Form 46 (Enrolled) Dataset | Contains data obtained from Form 46 - Leisure Time Physical Activity (Includes data on enrolled participants only) | 33060 | csv (4.96 MB) | |
Form 91 (Enrolled) Dataset | Contains data obtained from Form 91 - (Includes data on enrolled participants only) | 569 | csv (34.43 KB) | |
Form 71 (Enrolled) Dataset | Contains data obtained from Form 71 - Baseline Diet Prescription (Includes data on enrolled participants only) | 839 | csv (132.07 KB) | |
Form 23 (Enrolled) Dataset | Contains data obtained from Form 23 - Action Item Response (Includes data on enrolled participants only) | 21850 | csv (1.6 MB) | |
Form 98 (Enrolled) Dataset | Contains data obtained from Form 98 - (Includes data on enrolled participants only) | 9028 | csv (353.74 KB) | |
Form 13 (Enrolled) Dataset | Contains data obtained from Form 13 - Annual Follow-Up Info (Includes data on enrolled participants only) | 2400 | csv (381.54 KB) | |
Form 14 (Enrolled) Dataset | Contains data obtained from Form 14 - Reason Missed Follow-Ups (Includes data on enrolled participants only) | 82 | csv (9.75 KB) | |
Form 17 (Enrolled) Dataset | Contains data obtained from Form 17 - Central Lab Blood Urine Mail (Includes data on enrolled participants only) | 33524 | csv (3.31 MB) | |
Form 50 (Screened) Dataset | Contains data obtained from Form 50 - Recruitment Baseline Patients (Includes data on all screened individuals) | 2655 | csv (158.6 KB) | |
Form 18 (Enrolled) Dataset | Contains data obtained from Form 18 - EKG Mail (Includes data on enrolled participants only) | 3767 | csv (247.03 KB) | |
Form 65 (Enrolled) Dataset | Contains data obtained from Form 65 - Anthropometry (Includes data on enrolled participants only) | 9487 | csv (1.79 MB) | |
Form 66 (Enrolled) Dataset | Contains data obtained from Form 66 - NCC Phantom Matching (Includes data on enrolled participants only) | 107 | csv (7.87 KB) | |
Form 62 (Enrolled) Dataset | Contains data obtained from Form 62 - Recipe Form (Includes data on enrolled participants only) | 92 | csv (30.85 KB) | |
Form 07 (Enrolled) Dataset | Contains data obtained from Form 07 - Renal Diagnosis (Includes data on enrolled participants only) | 1434 | csv (129.89 KB) | |
Form 08 (Enrolled) Dataset | Contains data obtained from Form 08 - 2nd Screen After B3 or Dropout (Includes data on enrolled participants only) | 1935 | csv (273.61 KB) | |
Form 10 (Enrolled) Dataset | Contains data obtained from Form 10 - Unscheduled Medical (Includes data on enrolled participants only) | 1452 | csv (258.49 KB) | |
Form 01 (Enrolled) Dataset | Contains data obtained from Form 01 - Chart Screening (Includes data on enrolled participants only) | 1951 | csv (181.38 KB) | |
Form 78 (Enrolled) Dataset | Contains data obtained from Form 78 - Dietician Patient Care Time Log (Includes data on enrolled participants only) | 1882 | csv (248.13 KB) | |
Form 29 (Screened) Dataset | Contains data obtained from Form 29 - Economic Information (Includes data on all screened individuals) | 605 | csv (47.17 KB) | |
AJKD 2015 MDRD Dataset | Captures data on Beta trace protein and Beta 2 microglubulin concentrations (in mg/L | 800 | csv (19.02 KB) | |
Form 05 (Enrolled) Dataset | Contains data obtained from Form 05 - Monthly Exam (Includes data on enrolled participants only) | 28903 | csv (4.78 MB) | |
Form 03 (Enrolled) Dataset | Contains data obtained from Form 03 - Screening (Includes data on enrolled participants only) | 2012 | csv (515.15 KB) | |
Form 74 (Enrolled) Dataset | Contains data obtained from Form 74 - Pill Count (Includes data on enrolled participants only) | 5150 | csv (657.48 KB) | |
Form 02 (Screened) Dataset | Contains data obtained from Form 02 - Eligible No Screening Visit (Includes data on all screened individuals) | 949 | csv (50.99 KB) | |
Form 72 (Enrolled) Dataset | Contains data obtained from Form 72 - Study Diet Prescription (Includes data on enrolled participants only) | 270 | csv (36.52 KB) | |
Form 76 (Enrolled) Dataset | Contains data obtained from Form 76 - Diet Satisfaction Questions (Includes data on enrolled participants only) | 22334 | csv (3.78 MB) | |
Form 90 (Enrolled) Dataset | Contains data obtained from Form 90 - (Includes data on enrolled participants only) | 578 | csv (26.63 KB) | |
Form 97 (Enrolled) Dataset | Contains data obtained from Form 97 - (Includes data on enrolled participants only) | 71 | csv (4.1 KB) | |
Form 70 (Enrolled) Dataset | Contains data obtained from Form 70 - Anthropometry Monitoring Obsolete (Includes data on enrolled participants only) | 722 | csv (81.7 KB) | |
Form 94 (Enrolled) Dataset | Contains data obtained from Form 94 - (Includes data on enrolled participants only) | 42000 | csv (1.77 MB) | |
Form 93 (Enrolled) Dataset | Contains data obtained from Form 93 - (Includes data on enrolled participants only) | 9049 | csv (377.2 KB) | |
Form 95 (Enrolled) Dataset | Contains data obtained from Form 95 - (Includes data on enrolled participants only) | 9675 | csv (393.3 KB) | |
Form 92 (Enrolled) Dataset | Contains data obtained from Form 92 - (Includes data on enrolled participants only) | 3060 | csv (121.81 KB) | |
Form 24 (Screened) Dataset | Contains data obtained from Form 24 - Data Out-of-Range (Includes data on all screened individuals) | 37 | csv (3.67 KB) | |
Form 15 (Screened) Dataset | Contains data obtained from Form 15 - Death Notification (Includes data on all screened individuals) | 1 | csv (233 B) | |
Form 25 (Screened) Dataset | Contains data obtained from Form 25 - Data Change (Includes data on all screened individuals) | 662 | csv (62.08 KB) | |
Form 80 (Enrolled) Dataset | Contains data obtained from Form 80 - Special Food Products Order (Includes data on enrolled participants only) | 204 | csv (38.43 KB) | |
Form 54 (Enrolled) Dataset | Contains data obtained from Form 54 - Food Record 24h Packing Slip (Includes data on enrolled participants only) | 466 | csv (32 KB) | |
Form 25 (Enrolled) Dataset | Contains data obtained from Form 25 - Data Change (Includes data on enrolled participants only) | 6380 | csv (596.97 KB) | |
Form 07 (Screened) Dataset | Contains data obtained from Form 07 - Renal Diagnosis (Includes data on all screened individuals) | 4 | csv (664 B) | |
Form 77 (Enrolled) Dataset | Contains data obtained from Form 77 - Compliance Counselling Summary (Includes data on enrolled participants only) | 25082 | csv (2.41 MB) | |
Form 29 (Enrolled) Dataset | Contains data obtained from Form 29 - Study C Assignment (Includes data on enrolled participants only) | 3979 | csv (331.77 KB) | |
Form 03 (Screened) Dataset | Contains data obtained from Form 03 - Screening (Includes data on all screened individuals) | 2745 | csv (689.18 KB) | |
Form 50 (Enrolled) Dataset | Contains data obtained from Form 50 - Study 3 Enrollment Mailing Form (Includes data on enrolled participants only) | 1935 | csv (115.24 KB) | |
Form 02 (Enrolled) Dataset | Contains data obtained from Form 02 - Eligible No Screening Visit (Includes data on enrolled participants only) | csv (109 B) | ||
Form 21 (Enrolled) Dataset | Contains data obtained from Form 21 - Clinical Center CAP QC (Includes data on enrolled participants only) | 53 | csv (7.5 KB) | |
Form 73 (Enrolled) Dataset | Contains data obtained from Form 73 - Special Dietary Consideration (Includes data on enrolled participants only) | 2994 | csv (394.19 KB) | |
Form 44 (Enrolled) Dataset | Contains data obtained from Form 44 - Local Blood Pressure (Includes data on enrolled participants only) | 693 | csv (147.62 KB) | |
Form 96 (Enrolled) Dataset | Contains data obtained from Form 96 - (Includes data on enrolled participants only) | 3690 | csv (226.65 KB) | |
Form 48 (Enrolled) Dataset | Contains data obtained from Form 48 - Other Evidence Renal Disease (Includes data on enrolled participants only) | 2756 | csv (428.14 KB) | |
Form 12 (Enrolled) Dataset | Contains data obtained from Form 12 - Abbreviated Follow-Up (Includes data on enrolled participants only) | 620 | csv (146.44 KB) | |
Form 51 (Screened) Dataset | Contains data obtained from Form 51 - Other Evidence Renal Disease (Includes data on all screened individuals) | 87 | csv (9.3 KB) | |
Form 11 (Enrolled) Dataset | Contains data obtained from Form 11 - Stop Point (Includes data on enrolled participants only) | 265 | csv (31.16 KB) | |
Form 64 (Enrolled) Dataset | Contains data obtained from Form 64 - Three-Day Food Record Form (Includes data on enrolled participants only) | 42375 | csv (13.76 MB) | |
Form 09 (Enrolled) Dataset | Contains data obtained from Form 09 - Randomization (Includes data on enrolled participants only) | 840 | csv (53.29 KB) | |
Form 16 (Enrolled) Dataset | Contains data obtained from Form 16 - GFR Determination (Includes data on enrolled participants only) | 11449 | csv (2.39 MB) | |
Form 15 (Enrolled) Dataset | Contains data obtained from Form 15 - Death Notification (Includes data on enrolled participants only) | 61 | csv (4.46 KB) | |
Form 19 (Enrolled) Dataset | Contains data obtained from Form 19 - Amino Acid Mail (Includes data on enrolled participants only) | 5093 | csv (369.78 KB) | |
Form 41 (Screened) Dataset | Contains data obtained from Form 41 - Death Review (Includes data on all screened individuals) | 1 | csv (226 B) | |
Form 06 (Enrolled) Dataset | Contains data obtained from Form 06 - Local Lab Measurement (Includes data on enrolled participants only) | 16234 | csv (2.41 MB) | |
Form 98 (Screened) Dataset | Contains data obtained from Form 98 (Includes data on all screened individuals) | 10989 | csv (430.79 KB) | |
Form 46 (Screened) Dataset | Contains data obtained from Form 46 - Local Blood Pressure (Includes data on all screened individuals) | 2734 | csv (421.43 KB) | |
Form 53 (Enrolled) Dataset | Contains data obtained from Form 53 - Close Out Nutrition Prescription Form (Includes data on enrolled participants only) | 620 | csv (73.14 KB) | |
Form 55 (Enrolled) Dataset | Contains data obtained from Form 55 - Nutrition Cover Sheet (Includes data on enrolled participants only) | 107 | csv (25.59 KB) | |
Form 28 (Enrolled) Dataset | Contains data obtained from Form 28 - Transfer (Includes data on enrolled participants only) | 6672 | csv (1.79 MB) | |
Form 26 (Enrolled) Dataset | Contains data obtained from Form 26 - Patient Symptom Monthly (Includes data on enrolled participants only) | 27973 | csv (3.87 MB) | |
NEJM 2012 MDRD Dataset | Captures data on Serum Creatinine and Serum Cystatin C concentrations in mg/L | 1046 | csv (30.07 KB) | |
Form 51 (Enrolled) Dataset | Contains data obtained from Form 51 - Blood Buffy Coat SOP (Includes data on enrolled participants only) | 78 | csv (8.36 KB) | |
Form 47 (Enrolled) Dataset | Contains data obtained from Form 47 - Recruitment Baseline Patients (Includes data on enrolled participants only) | 3313 | csv (412.52 KB) | |
Form 22 (Enrolled) Dataset | Contains data obtained from Form 22 - Central Lab QC ID Match (Includes data on enrolled participants only) | 1110 | csv (81.87 KB) | |
Form 45 (Enrolled) Dataset | Contains data obtained from Form 45 - Study F (Includes data on enrolled participants only) | 155 | csv (19.23 KB) | |
Form 49 (Enrolled) Dataset | Contains data obtained from Form 49 - Blood Pressure Treatment (Includes data on enrolled participants only) | 1022 | csv (128.12 KB) | |
Form 24 (Enrolled) Dataset | Contains data obtained from Form 24 - Data Out-of-Range (Includes data on enrolled participants only) | 1162 | csv (106.1 KB) | |
Form 20 (Enrolled) Dataset | Contains data obtained from Form 20 - Local Lab QC (Includes data on enrolled participants only) | 112 | csv (9.98 KB) | |
Form 41 (Enrolled) Dataset | Contains data obtained from Form 41 - Follow-Up Nutrition Survey (Includes data on enrolled participants only) | 24 | csv (1.7 KB) | |
Form 39 (Enrolled) Dataset | Contains data obtained from Form 39 - Death Review (Includes data on enrolled participants only) | 58 | csv (7.14 KB) | |
MDRD Longitudinal Dataset | Captures data on B2M, BTP, Creatinine, Cystatin C concentrations at 12/24 months in mg/L and mg/dL for creatinine | 317 | csv (49.92 KB) | |
Form 40 (Enrolled) Dataset | Contains data obtained from Form 40 - GFR (Glomerular Filtration Rate) (Includes data on enrolled participants only) | 104 | csv (9.28 KB) | |
Form 43 (Enrolled) Dataset | Contains data obtained from Form 43 - Close Out Non-randomized Patient Survey (Includes data on enrolled participants only) | 690 | csv (53.27 KB) | |
Form 42 (Enrolled) Dataset | Contains data obtained from Form 42 - Follow-Up Randomized Patient Survey (Includes data on enrolled participants only) | 10811 | csv (2.79 MB) | |
Form 77 (Screened) Dataset | Contains data obtained from Form 77 - Dietician Patient Care Time Log (Includes data on all screened individuals) | 68 | csv (6.57 KB) | |
Form 78 (Screened) Dataset | Contains data obtained from Form 78 - Nutrition History Questions (Includes data on all screened individuals) | 1916 | csv (252.57 KB) | |
Analysis 2009 MDRD Dataset | Captures data on Serum Creatinine concentration in mg/L | 1628 | csv (31.59 KB) | |
Form 31 (Enrolled) Dataset | Contains data obtained from Form 31 - Blood Analysis Report Biochem Lab (Includes data on enrolled participants only) | 19 | csv (1.61 KB) | |
Form 37 (Enrolled) Dataset | Contains data obtained from Form 37 - Peer Group Range Form (Includes data on enrolled participants only) | 840 | csv (86.06 KB) | |
Form 30 (Enrolled) Dataset | Contains data obtained from Form 30 - 24h Urine Report Biochem Lab (Includes data on enrolled participants only) | 18 | csv (1.32 KB) | |
Form 38 (Enrolled) Dataset | Contains data obtained from Form 38 - Stop Point Review (Includes data on enrolled participants only) | 308 | csv (27.06 KB) | |
Form 32 (Enrolled) Dataset | Contains data obtained from Form 32 - Central Lab CAP QC (Includes data on enrolled participants only) | 27315 | csv (4.78 MB) | |
Form 36 (Enrolled) Dataset | Contains data obtained from Form 36 - Safety Variable Review (Includes data on enrolled participants only) | 5168 | csv (1.45 MB) | |
Form 33 (Enrolled) Dataset | Contains data obtained from Form 33 - Central Lab EKG (Includes data on enrolled participants only) | 17428 | csv (3.21 MB) | |
Form 35 (Enrolled) Dataset | Contains data obtained from Form 35 - Study A & B Randomization (Includes data on enrolled participants only) | 10036 | csv (1.05 MB) | |
Form 34 (Enrolled) Dataset | Contains data obtained from Form 34 - Amino Acid Data (Includes data on enrolled participants only) | 11 | csv (8.51 KB) | |
MDRD CRP Dataset | Captures data on C-reactive protein concentration | 803 | csv (11.86 KB); sas7bdat (32 KB) | |
Baseline Dataset | Captures all data collected at baseline | 5338 | sas7bdat (6.63 MB); csv (2.92 MB) | |
Events Dataset | Captures data on all major medical events that occur during the MDRD study | 840 | sas7bdat (121 KB); csv (77.57 KB) | |
Analysis Dataset | Captures analysis data used for the reporting of study information and results | 25963 | sas7bdat (18.95 MB); csv (10.8 MB) |
Specimen | Count |
---|---|
24 h urine | 2344 |
Buffy Coat | 407 |
Plasma | 2382 |
Serum | 10300 |
Urine | 15569 |