An official website of the United States government

This repository is under review for potential modification in compliance with Administration directives.
Citation
Beck, Gerald (2020). Modification of Diet in Renal Disease (MDRD) (Version 4) [Dataset] NIDDK Central Repository. https://doi.org/10.58020/h754-eg50
Data Availability Statement
Data from Modification of Diet in Renal Disease (MDRD) [(Version 4) https://doi.org/10.58020/h754-eg50] reported here are available for request at the NIDDK Central Repository (NIDDK-CR) website, Resources for Research (R4R), https://repository.niddk.nih.gov/.
Acknowledgement Statement
The MDRD study was conducted by the study investigators and supported by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The resources from the MDRD (https://doi.org/10.58020/h754-eg50) study reported here were supplied by NIDDK Central Repository (NIDDK-CR) and are available for request at https://repository.niddk.nih.gov. This manuscript was not prepared under the auspices of the MDRD study and does not necessarily reflect the opinions or views of the MDRD study, NIDDK-CR, or NIDDK.
Data Package Version
Version 4 (Updated on: Nov 18, 2020)
Resource Availability
  • Data Available for Request
  • Specimens Available for Request
Publications
Explore publications resulting from the use of study resources
View publications (80)

General Description

The Modification of Diet in Renal Disease (MDRD) study consisted of two randomized clinical trials that investigated whether protein restriction and control of blood pressure had an effect on the progression of chronic kidney disease (CKD). The study tested two hypotheses—that (1) a reduction in dietary protein and phosphorous intake and (2) the maintenance of blood pressure at a level below that usually recommended safely and effectively delays the progression of CKD.

In study 1, 585 patients with glomerular filtration rates (GFR) of 25-55 ml/min/1.73 m2 of body-surface area were randomly assigned to a usual-protein diet or a low-protein diet (1.3 or 0.58 g of protein per kilogram of body weight per day) and to a usual- or a low-blood-pressure group (mean arterial pressure, 107 or 92 mm Hg). In study 2, 255 patients with GFR of 13 to 24 ml/min/1.73 m2 were randomly assigned to the low-protein diet (0.58 g per kilogram per day) or a very-low-protein diet (0.28 g per kilogram per day) with a keto acid-amino acid supplement, and a usual- or a low-blood-pressure group (same values as those in study 1). The length of follow-up varied from 18-to-45-months, with monthly evaluations of the patients. The primary outcome was the change in GFR rate over time. The study found that among patients with moderate renal insufficiency, the slower decline in renal function that started four months after the introduction of a low-protein diet suggests a small benefit of this dietary intervention. Among patients with more severe renal insufficiency, a very-low-protein diet, as compared with a low-protein diet, did not significantly slow the progression of renal disease.

Objectives

The MDRD study aimed to investigate the effect of protein restriction and blood pressure control on the progression of disease in patients with chronic renal diseases. The study hypothesized that a reduction in dietary protein and phosphorous intake and the maintenance of blood pressure below recommended levels would delay the progression of renal disease.

Outcome Measure

The primary outcome measure used to assess renal function was the rate of change in glomerular filtration rate over time.

Eligibility Criteria

The following enrollment criteria were used:

  • Aged 18 to 70 years
  • Serum creatinine concentration of 1.2-7.0 mg/deciliter in women and 1.4-7.0 mg/deciliter in men or a creatinine clearance of less than 70 ml/min/1.73 m2 of body-surface area
  • Mean arterial pressure (MAP) of 125 mm Hg or less

Glomerular filtration rate (GFR) was used to separate patients into study 1 or study 2. During a three-month base-line period, patients were deemed eligible for study 1 if their GFR was 25-55 ml/min/1.73 m2, and their dietary protein intake was ≥ 0.9 g/kg of body weight per day. Patients were eligible for study 2 if their GFR was 13-24 ml/min/1.73 m2, irrespective of protein intake.

Exclusion criteria are documented in the protocol

Outcome

Among patients with moderate renal insufficiency, the slower decline in renal function that started four months after the introduction of a low-protein diet suggests a small benefit of this dietary intervention. Among patients with more severe renal insufficiency, a very-low-protein diet, as compared with a low-protein diet, did not significantly slow the progression of renal disease. Overall, a low blood pressure goal was not shown to have benefit over the higher goal. Among persons with more pronounced proteinuria at baseline had a significantly slower rate of decline in GFR

Research Area

Nutrition, Multidisciplinary Research, Kidney Disease

Study Type

Interventional

Study Sites

15

Study Start Date

1988-10

Study End Date

2016-01

Condition

Chronic Kidney Disease

Keywords

Low-Protein Diet, Blood Pressure, Protien Restriction, Disease Progression, Glomerular Filtration Rate (GFR), Randomized Clinical Trial, Phosphorous Intake, Chronic Renal Insufficiency

NIDDK Division

Division of Kidney, Urologic, and Hematologic Diseases

1,795
Participants

Target Population
Adults

Sex

Bar chart with 2 data series.
The chart has 1 X axis displaying categories.
The chart has 1 Y axis displaying values. Data ranges from 710 to 1085.
End of interactive chart.

Age

Bar chart with 4 data series.
The chart has 1 X axis displaying categories.
The chart has 1 Y axis displaying values. Data ranges from 47 to 916.
End of interactive chart.

Race

Bar chart with 6 data series.
The chart has 1 X axis displaying categories.
The chart has 1 Y axis displaying values. Data ranges from 3 to 1429.
End of interactive chart.

Ethnicity

Bar chart with 2 data series.
The chart has 1 X axis displaying categories.
The chart has 1 Y axis displaying values. Data ranges from 94 to 1701.
End of interactive chart.

Location

Bar chart with 15 data series.
The chart has 1 X axis displaying categories.
The chart has 1 Y axis displaying values. Data ranges from 86 to 157.
End of interactive chart.

Public Documents Table
Document Name
Description
Document Type
File Format
Compliance
Download
MDRD Data Dictionary
Data Dictionary used as a collection of metadata - defines the variable contents of each datasetCodebook/Data DictionaryPDF
If you need accessible versions of documents, please email your request to NIDDK-CRsupport@niddk.nih.gov

Permitted Use(s) of the Resources
  • Use is allowed for health, medical, or biomedical research purposes
Non-Public Documents (96)
Non-Public Documents Table
Document Name
Description
Document Type
File Format
Form 28 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 28 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 29 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 29 (Enrolled) DatasetFormats/Dataset InstructionSAS
Analysis Datasets SAS Formats
SAS Formats file that provides the values and value labels for the variables in MDRD Analysis datasetsFormats/Dataset InstructionTXT
Form 01 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 01 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 01 (Screened) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 01 (Screened) DatasetFormats/Dataset InstructionSAS
Form 02 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 02 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 02 (Screened) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 02 (Screened) DatasetFormats/Dataset InstructionSAS
Form 03 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 03 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 03 (Screened) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 03 (Screened) DatasetFormats/Dataset InstructionSAS
Form 04 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 04 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 05 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 05 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 06 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 06 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 07 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 07 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 07 (Screened) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 07 (Screened) DatasetFormats/Dataset InstructionSAS
Form 08 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 08 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 09 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 09 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 10 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 10 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 11 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 11 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 12 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 12 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 13 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 13 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 14 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 14 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 15 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 15 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 15 (Screened) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 15 (Screened) DatasetFormats/Dataset InstructionSAS
Form 16 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 16 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 17 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 17 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 18 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 18 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 19 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 19 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 20 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 20 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 21 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 21 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 22 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 22 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 23 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 23 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 24 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 24 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 24 (Screened) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 24 (Screened) DatasetFormats/Dataset InstructionSAS
Form 25 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 25 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 25 (Screened) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 25 (Screened) DatasetFormats/Dataset InstructionSAS
Form 26 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 26 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 27 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 27 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 29 (Screened) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 29 (Screened) DatasetFormats/Dataset InstructionSAS
Form 30 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 30 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 31 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 31 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 32 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 32 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 33 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 33 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 34 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 34 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 35 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 35 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 36 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 36 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 37 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 37 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 38 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 38 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 39 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 39 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 40 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 40 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 41 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 41 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 41 (Screened) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 41 (Screened) DatasetFormats/Dataset InstructionSAS
Form 42 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 42 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 43 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 43 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 44 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 44 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 45 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 45 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 46 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 46 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 46 (Screened) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 46 (Screened) DatasetFormats/Dataset InstructionSAS
Form 47 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 47 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 48 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 48 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 49 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 49 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 50 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 50 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 50 (Screened) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 50 (Screened) DatasetFormats/Dataset InstructionSAS
Form 51 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 51 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 51 (Screened) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 51 (Screened) DatasetFormats/Dataset InstructionSAS
Form 52 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 52 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 53 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 53 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 54 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 54 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 55 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 55 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 56 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 56 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 62 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 62 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 64 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 64 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 65 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 65 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 66 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 66 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 70 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 70 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 71 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 71 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 72 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 72 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 73 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 73 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 74 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 74 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 76 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 76 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 77 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 77 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 77 (Screened) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 77 (Screened) DatasetFormats/Dataset InstructionSAS
Form 78 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 78 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 78 (Screened) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 78 (Screened) DatasetFormats/Dataset InstructionSAS
Form 79 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 79 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 80 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 80 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 81 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 81 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 90 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 90 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 91 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 91 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 92 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 92 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 93 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 93 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 94 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 94 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 95 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 95 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 96 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 96 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 97 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 97 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 98 (Enrolled) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 98 (Enrolled) DatasetFormats/Dataset InstructionSAS
Form 98 (Screened) Dataset SAS Formats
SAS Formats file that provides the values and value labels for the variables in the Form 98 (Screened) DatasetFormats/Dataset InstructionSAS
Datasets (203)
Datasets Table
Dataset Name
Description
# of Records
# of Variables
File Format(s)
Form 81 (Enrolled) Dataset
Contains data obtained from Form 81 - Low Protein Entree (Includes data on enrolled participants only)402csv (38.23 KB)
Form 79 (Enrolled) Dataset
Contains data obtained from Form 79 - Nutrition History Questions (Includes data on enrolled participants only)11676csv (1.4 MB)
Form 27 (Enrolled) Dataset
Contains data obtained from Form 27 - Economic Information (Includes data on enrolled participants only)5440csv (1.01 MB)
Form 04 (Enrolled) Dataset
Contains data obtained from Form 04 - Demographic & Baseline Exam (Includes data on enrolled participants only)1935csv (725.92 KB)
Form 56 (Enrolled) Dataset
Contains data obtained from Form 56 - Food Record Form (Includes data on enrolled participants only)2291csv (237.1 KB)
Form 52 (Enrolled) Dataset
Contains data obtained from Form 52 - Dialysis Delivery Draft Form (Includes data on enrolled participants only)6370csv (624.43 KB)
Form 01 (Screened) Dataset
Contains data obtained from Form 01 - Chart Screening (Includes data on all screened individuals)4443csv (417.2 KB)
Form 46 (Enrolled) Dataset
Contains data obtained from Form 46 - Leisure Time Physical Activity (Includes data on enrolled participants only)33060csv (4.96 MB)
Form 91 (Enrolled) Dataset
Contains data obtained from Form 91 - (Includes data on enrolled participants only)569csv (34.43 KB)
Form 71 (Enrolled) Dataset
Contains data obtained from Form 71 - Baseline Diet Prescription (Includes data on enrolled participants only)839csv (132.07 KB)
Form 23 (Enrolled) Dataset
Contains data obtained from Form 23 - Action Item Response (Includes data on enrolled participants only)21850csv (1.6 MB)
Form 98 (Enrolled) Dataset
Contains data obtained from Form 98 - (Includes data on enrolled participants only)9028csv (353.74 KB)
Form 13 (Enrolled) Dataset
Contains data obtained from Form 13 - Annual Follow-Up Info (Includes data on enrolled participants only)2400csv (381.54 KB)
Form 14 (Enrolled) Dataset
Contains data obtained from Form 14 - Reason Missed Follow-Ups (Includes data on enrolled participants only)82csv (9.75 KB)
Form 17 (Enrolled) Dataset
Contains data obtained from Form 17 - Central Lab Blood Urine Mail (Includes data on enrolled participants only)33524csv (3.31 MB)
Form 50 (Screened) Dataset
Contains data obtained from Form 50 - Recruitment Baseline Patients (Includes data on all screened individuals)2655csv (158.6 KB)
Form 18 (Enrolled) Dataset
Contains data obtained from Form 18 - EKG Mail (Includes data on enrolled participants only)3767csv (247.03 KB)
Form 65 (Enrolled) Dataset
Contains data obtained from Form 65 - Anthropometry (Includes data on enrolled participants only)9487csv (1.79 MB)
Form 66 (Enrolled) Dataset
Contains data obtained from Form 66 - NCC Phantom Matching (Includes data on enrolled participants only)107csv (7.87 KB)
Form 62 (Enrolled) Dataset
Contains data obtained from Form 62 - Recipe Form (Includes data on enrolled participants only)92csv (30.85 KB)
Form 07 (Enrolled) Dataset
Contains data obtained from Form 07 - Renal Diagnosis (Includes data on enrolled participants only)1434csv (129.89 KB)
Form 08 (Enrolled) Dataset
Contains data obtained from Form 08 - 2nd Screen After B3 or Dropout (Includes data on enrolled participants only)1935csv (273.61 KB)
Form 10 (Enrolled) Dataset
Contains data obtained from Form 10 - Unscheduled Medical (Includes data on enrolled participants only)1452csv (258.49 KB)
Form 01 (Enrolled) Dataset
Contains data obtained from Form 01 - Chart Screening (Includes data on enrolled participants only)1951csv (181.38 KB)
Form 78 (Enrolled) Dataset
Contains data obtained from Form 78 - Dietician Patient Care Time Log (Includes data on enrolled participants only)1882csv (248.13 KB)
Form 29 (Screened) Dataset
Contains data obtained from Form 29 - Economic Information (Includes data on all screened individuals)605csv (47.17 KB)
AJKD 2015 MDRD Dataset
Captures data on Beta trace protein and Beta 2 microglubulin concentrations (in mg/L800csv (19.02 KB)
Form 05 (Enrolled) Dataset
Contains data obtained from Form 05 - Monthly Exam (Includes data on enrolled participants only)28903csv (4.78 MB)
Form 03 (Enrolled) Dataset
Contains data obtained from Form 03 - Screening (Includes data on enrolled participants only)2012csv (515.15 KB)
Form 74 (Enrolled) Dataset
Contains data obtained from Form 74 - Pill Count (Includes data on enrolled participants only)5150csv (657.48 KB)
Form 02 (Screened) Dataset
Contains data obtained from Form 02 - Eligible No Screening Visit (Includes data on all screened individuals)949csv (50.99 KB)
Form 72 (Enrolled) Dataset
Contains data obtained from Form 72 - Study Diet Prescription (Includes data on enrolled participants only)270csv (36.52 KB)
Form 76 (Enrolled) Dataset
Contains data obtained from Form 76 - Diet Satisfaction Questions (Includes data on enrolled participants only)22334csv (3.78 MB)
Form 90 (Enrolled) Dataset
Contains data obtained from Form 90 - (Includes data on enrolled participants only)578csv (26.63 KB)
Form 97 (Enrolled) Dataset
Contains data obtained from Form 97 - (Includes data on enrolled participants only)71csv (4.1 KB)
Form 70 (Enrolled) Dataset
Contains data obtained from Form 70 - Anthropometry Monitoring Obsolete (Includes data on enrolled participants only)722csv (81.7 KB)
Form 94 (Enrolled) Dataset
Contains data obtained from Form 94 - (Includes data on enrolled participants only)42000csv (1.77 MB)
Form 93 (Enrolled) Dataset
Contains data obtained from Form 93 - (Includes data on enrolled participants only)9049csv (377.2 KB)
Form 95 (Enrolled) Dataset
Contains data obtained from Form 95 - (Includes data on enrolled participants only)9675csv (393.3 KB)
Form 92 (Enrolled) Dataset
Contains data obtained from Form 92 - (Includes data on enrolled participants only)3060csv (121.81 KB)
Form 24 (Screened) Dataset
Contains data obtained from Form 24 - Data Out-of-Range (Includes data on all screened individuals)37csv (3.67 KB)
Form 15 (Screened) Dataset
Contains data obtained from Form 15 - Death Notification (Includes data on all screened individuals)1csv (233 B)
Form 25 (Screened) Dataset
Contains data obtained from Form 25 - Data Change (Includes data on all screened individuals)662csv (62.08 KB)
Form 80 (Enrolled) Dataset
Contains data obtained from Form 80 - Special Food Products Order (Includes data on enrolled participants only)204csv (38.43 KB)
Form 54 (Enrolled) Dataset
Contains data obtained from Form 54 - Food Record 24h Packing Slip (Includes data on enrolled participants only)466csv (32 KB)
Form 25 (Enrolled) Dataset
Contains data obtained from Form 25 - Data Change (Includes data on enrolled participants only)6380csv (596.97 KB)
Form 07 (Screened) Dataset
Contains data obtained from Form 07 - Renal Diagnosis (Includes data on all screened individuals)4csv (664 B)
Form 77 (Enrolled) Dataset
Contains data obtained from Form 77 - Compliance Counselling Summary (Includes data on enrolled participants only)25082csv (2.41 MB)
Form 29 (Enrolled) Dataset
Contains data obtained from Form 29 - Study C Assignment (Includes data on enrolled participants only)3979csv (331.77 KB)
Form 03 (Screened) Dataset
Contains data obtained from Form 03 - Screening (Includes data on all screened individuals)2745csv (689.18 KB)
Form 50 (Enrolled) Dataset
Contains data obtained from Form 50 - Study 3 Enrollment Mailing Form (Includes data on enrolled participants only)1935csv (115.24 KB)
Form 02 (Enrolled) Dataset
Contains data obtained from Form 02 - Eligible No Screening Visit (Includes data on enrolled participants only)csv (109 B)
Form 21 (Enrolled) Dataset
Contains data obtained from Form 21 - Clinical Center CAP QC (Includes data on enrolled participants only)53csv (7.5 KB)
Form 73 (Enrolled) Dataset
Contains data obtained from Form 73 - Special Dietary Consideration (Includes data on enrolled participants only)2994csv (394.19 KB)
Form 44 (Enrolled) Dataset
Contains data obtained from Form 44 - Local Blood Pressure (Includes data on enrolled participants only)693csv (147.62 KB)
Form 96 (Enrolled) Dataset
Contains data obtained from Form 96 - (Includes data on enrolled participants only)3690csv (226.65 KB)
Form 48 (Enrolled) Dataset
Contains data obtained from Form 48 - Other Evidence Renal Disease (Includes data on enrolled participants only)2756csv (428.14 KB)
Form 12 (Enrolled) Dataset
Contains data obtained from Form 12 - Abbreviated Follow-Up (Includes data on enrolled participants only)620csv (146.44 KB)
Form 51 (Screened) Dataset
Contains data obtained from Form 51 - Other Evidence Renal Disease (Includes data on all screened individuals)87csv (9.3 KB)
Form 11 (Enrolled) Dataset
Contains data obtained from Form 11 - Stop Point (Includes data on enrolled participants only)265csv (31.16 KB)
Form 64 (Enrolled) Dataset
Contains data obtained from Form 64 - Three-Day Food Record Form (Includes data on enrolled participants only)42375csv (13.76 MB)
Form 09 (Enrolled) Dataset
Contains data obtained from Form 09 - Randomization (Includes data on enrolled participants only)840csv (53.29 KB)
Form 16 (Enrolled) Dataset
Contains data obtained from Form 16 - GFR Determination (Includes data on enrolled participants only)11449csv (2.39 MB)
Form 15 (Enrolled) Dataset
Contains data obtained from Form 15 - Death Notification (Includes data on enrolled participants only)61csv (4.46 KB)
Form 19 (Enrolled) Dataset
Contains data obtained from Form 19 - Amino Acid Mail (Includes data on enrolled participants only)5093csv (369.78 KB)
Form 41 (Screened) Dataset
Contains data obtained from Form 41 - Death Review (Includes data on all screened individuals)1csv (226 B)
Form 06 (Enrolled) Dataset
Contains data obtained from Form 06 - Local Lab Measurement (Includes data on enrolled participants only)16234csv (2.41 MB)
Form 98 (Screened) Dataset
Contains data obtained from Form 98 (Includes data on all screened individuals)10989csv (430.79 KB)
Form 46 (Screened) Dataset
Contains data obtained from Form 46 - Local Blood Pressure (Includes data on all screened individuals)2734csv (421.43 KB)
Form 53 (Enrolled) Dataset
Contains data obtained from Form 53 - Close Out Nutrition Prescription Form (Includes data on enrolled participants only)620csv (73.14 KB)
Form 55 (Enrolled) Dataset
Contains data obtained from Form 55 - Nutrition Cover Sheet (Includes data on enrolled participants only)107csv (25.59 KB)
Form 28 (Enrolled) Dataset
Contains data obtained from Form 28 - Transfer (Includes data on enrolled participants only)6672csv (1.79 MB)
Form 26 (Enrolled) Dataset
Contains data obtained from Form 26 - Patient Symptom Monthly (Includes data on enrolled participants only)27973csv (3.87 MB)
NEJM 2012 MDRD Dataset
Captures data on Serum Creatinine and Serum Cystatin C concentrations in mg/L1046csv (30.07 KB)
Form 51 (Enrolled) Dataset
Contains data obtained from Form 51 - Blood Buffy Coat SOP (Includes data on enrolled participants only)78csv (8.36 KB)
Form 47 (Enrolled) Dataset
Contains data obtained from Form 47 - Recruitment Baseline Patients (Includes data on enrolled participants only)3313csv (412.52 KB)
Form 22 (Enrolled) Dataset
Contains data obtained from Form 22 - Central Lab QC ID Match (Includes data on enrolled participants only)1110csv (81.87 KB)
Form 45 (Enrolled) Dataset
Contains data obtained from Form 45 - Study F (Includes data on enrolled participants only)155csv (19.23 KB)
Form 49 (Enrolled) Dataset
Contains data obtained from Form 49 - Blood Pressure Treatment (Includes data on enrolled participants only)1022csv (128.12 KB)
Form 24 (Enrolled) Dataset
Contains data obtained from Form 24 - Data Out-of-Range (Includes data on enrolled participants only)1162csv (106.1 KB)
Form 20 (Enrolled) Dataset
Contains data obtained from Form 20 - Local Lab QC (Includes data on enrolled participants only)112csv (9.98 KB)
Form 41 (Enrolled) Dataset
Contains data obtained from Form 41 - Follow-Up Nutrition Survey (Includes data on enrolled participants only)24csv (1.7 KB)
Form 39 (Enrolled) Dataset
Contains data obtained from Form 39 - Death Review (Includes data on enrolled participants only)58csv (7.14 KB)
MDRD Longitudinal Dataset
Captures data on B2M, BTP, Creatinine, Cystatin C concentrations at 12/24 months in mg/L and mg/dL for creatinine317csv (49.92 KB)
Form 40 (Enrolled) Dataset
Contains data obtained from Form 40 - GFR (Glomerular Filtration Rate) (Includes data on enrolled participants only)104csv (9.28 KB)
Form 43 (Enrolled) Dataset
Contains data obtained from Form 43 - Close Out Non-randomized Patient Survey (Includes data on enrolled participants only)690csv (53.27 KB)
Form 42 (Enrolled) Dataset
Contains data obtained from Form 42 - Follow-Up Randomized Patient Survey (Includes data on enrolled participants only)10811csv (2.79 MB)
Form 77 (Screened) Dataset
Contains data obtained from Form 77 - Dietician Patient Care Time Log (Includes data on all screened individuals)68csv (6.57 KB)
Form 78 (Screened) Dataset
Contains data obtained from Form 78 - Nutrition History Questions (Includes data on all screened individuals)1916csv (252.57 KB)
Analysis 2009 MDRD Dataset
Captures data on Serum Creatinine concentration in mg/L1628csv (31.59 KB)
Form 31 (Enrolled) Dataset
Contains data obtained from Form 31 - Blood Analysis Report Biochem Lab (Includes data on enrolled participants only)19csv (1.61 KB)
Form 37 (Enrolled) Dataset
Contains data obtained from Form 37 - Peer Group Range Form (Includes data on enrolled participants only)840csv (86.06 KB)
Form 30 (Enrolled) Dataset
Contains data obtained from Form 30 - 24h Urine Report Biochem Lab (Includes data on enrolled participants only)18csv (1.32 KB)
Form 38 (Enrolled) Dataset
Contains data obtained from Form 38 - Stop Point Review (Includes data on enrolled participants only)308csv (27.06 KB)
Form 32 (Enrolled) Dataset
Contains data obtained from Form 32 - Central Lab CAP QC (Includes data on enrolled participants only)27315csv (4.78 MB)
Form 36 (Enrolled) Dataset
Contains data obtained from Form 36 - Safety Variable Review (Includes data on enrolled participants only)5168csv (1.45 MB)
Form 33 (Enrolled) Dataset
Contains data obtained from Form 33 - Central Lab EKG (Includes data on enrolled participants only)17428csv (3.21 MB)
Form 35 (Enrolled) Dataset
Contains data obtained from Form 35 - Study A & B Randomization (Includes data on enrolled participants only)10036csv (1.05 MB)
Form 34 (Enrolled) Dataset
Contains data obtained from Form 34 - Amino Acid Data (Includes data on enrolled participants only)11csv (8.51 KB)
MDRD CRP Dataset
Captures data on C-reactive protein concentration803csv (11.86 KB); sas7bdat (32 KB)
Baseline Dataset
Captures all data collected at baseline5338sas7bdat (6.63 MB); csv (2.92 MB)
Events Dataset
Captures data on all major medical events that occur during the MDRD study840sas7bdat (121 KB); csv (77.57 KB)
Analysis Dataset
Captures analysis data used for the reporting of study information and results25963sas7bdat (18.95 MB); csv (10.8 MB)
Specimens (31,002)
Specimens Table
Specimen
Count
24 h urine2344
Buffy Coat407
Plasma2382
Serum10300
Urine15569