An official website of the United States government
This repository is under review for potential modification in compliance with Administration directives.
Data from Longitudinal Assessment of Bariatric Surgery Sub-Study: Mechanisms for Improvement of Type 2 Diabetes Following Bariatric Surgery (LABS-3) [(Version 1) https://doi.org/10.58020/5m7c-5n84] reported here are available for request at the NIDDK Central Repository (NIDDK-CR) website, Resources for Research (R4R), https://repository.niddk.nih.gov/.
The LABS-3 study was conducted by the study investigators and supported by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The resources from the LABS-3 (https://doi.org/10.58020/5m7c-5n84) study reported here were supplied by NIDDK Central Repository (NIDDK-CR) and are available for request at https://repository.niddk.nih.gov. This manuscript was not prepared under the auspices of the LABS-3 study and does not necessarily reflect the opinions or views of the LABS-3 study, NIDDK-CR, or NIDDK.
Data Package Version
Version 1 (Updated on: Oct 02, 2025)
Resource Availability
- Data Available for Request
- Specimens Available for Request
General Description
The LABS-3 Psychosocial Issues and Bariatric Surgery study conducted an in-depth examination of the psychosocial aspects of surgery among a geographically, ethnically, and racially diverse sample of men and women undergoing bariatric surgery. The study had experts in the areas of psychopathology, eating behaviors, and quality of life to conduct a naturalistic study using state-of-the-art assessment tools, and documented the relationships among psychosocial factors over a three-year period to examine psychosocial predictors of surgical outcomes.
Primary Objectives
The primary objective was to prospectively assess psychosocial outcomes of bariatric surgery including examining psychological factors, feeding patterns, and eating problems in participants over time.
Secondary Objectives
The secondary objective was to evaluate psychopathological and behavioral variables that may impact outcomes and understand how these factors affect weight loss, weight regain, and psychosocial complications after surgery.
Outcome Measure
Outcome measures include changes in medical and psychosocial measures, and the mechanisms of psychosocial and eating behavior issues related to bariatric surgery.
Inclusion Criteria
- Participants at least 18 years of age who undergo bariatric surgery by a LABS certified surgeon
- Previous enrollment in LABS-1 and LABS-2
- BMI of greater than or equal to 35
Exclusion Criteria
- Informed consent not obtained
- Type 1 Diabetes Mellitus
- Unlikely to comply with follow-up protocol (e.g., geographically inaccessible for study visits)
- Unable to communicate with local study staff
Outcome
The study found that prevalence of any mental disorder was lower at years 4 and 5 post-surgery but not at 7 years. In addition, having a concurrent mood disorder was associated with greater weight gain post-surgery within the cohort. Other relationships between eating disorders, mental health, cognitive function, and bariatric surgery were variable.
Research Area
Nutrition, Multidisciplinary Research, Obesity
Study Type
Observational
Study Sites
3
Study Enrollment Start Date
2010-07
Study Enrollment End Date
2019-06
Data Collection Start Date
2010-07
Data Collection End Date
2019-06
Condition
Morbid Obesity
Medication or Intervention Agent
None
Procedure
Bariatric Surgery
Clinical Trials URL
Keywords
Bariatric Surgery, Cognitive Function, Mood Disorder, Eating Disorders, 30-Day Mortality, Mental Health Outcomes, Morbid Obesity, Comorbidities
NIDDK Division
Division of Digestive Diseases and Nutrition (DDN)
202
Participants
Target Population
Adults
Document Name | Description | Document Type | File Format | Compliance | Download |
|---|---|---|---|---|---|
If you need accessible versions of documents, please email your request to NIDDK-CRsupport@niddk.nih.gov
Permitted Use(s) of the Resources
- Use is allowed for health, medical, or biomedical research purposes
Non-Public Documents (39)
Document Name | Description | Document Type | File Format |
|---|---|---|---|
Datasets (44)
Dataset Name | Description | # of Records | # of Variables | File Format(s) |
|---|---|---|---|---|
Medical Weight Form (WGT3) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from Medical Weight Form | 65 | sas7bdat (128 KB); csv (3.96 KB) | |
Medications (MEDRX) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures medications data | 917 | csv (41.42 KB); sas7bdat (192 KB) | |
SF-36 Health Survey (SF36) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from SF-36 Health Survey | 84 | sas7bdat (128 KB); csv (9.26 KB) | |
Medication Form (MED) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from Medication Form | 230 | sas7bdat (192 KB); csv (27.97 KB) | |
Cued Go/No-Go - Raw (GORAW) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures cued go/no-go raw data | 25750 | sas7bdat (3.81 MB); csv (2.52 MB) | |
Beck Depression Inventory (BDI) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from Beck Depression Inventory | 90 | sas7bdat (128 KB); csv (7.27 KB) | |
Work Productivity and Activity Impairment (WPAI) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from Work Productivty and Activity Impairment Form | 101 | sas7bdat (128 KB); csv (5.05 KB) | |
Nutritional Data System Eating Grid (NDSEG) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from Nutritional Data System Eating Grid Form | 5504 | sas7bdat (2.06 MB); csv (719.21 KB) | |
Sensitivity to Punishment and Sensitivity to Reward (SPSRQ) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from Sensitivity to Punishment and Sensitivity to Reward Form | 112 | sas7bdat (128 KB); csv (9.47 KB) | |
Sexual Functioning Follow-Up (SFF) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from Sexual Functioning Follow-Up Form | 101 | sas7bdat (128 KB); csv (16.3 KB) | |
SCID - I/P Coding Sheet (SCIDC) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from SCID - I/P Coding Sheet | 202 | sas7bdat (448 KB); csv (79.63 KB) | |
Difficulties in Emotion Regulation Scale (DERS) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from Difficulties in Emotion Regulation Scale | 113 | sas7bdat (128 KB); csv (12.31 KB) | |
Affect Intensity Measure (AIM) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from Affect Intensity Measure Form | 113 | sas7bdat (128 KB); csv (13.27 KB) | |
SCID - 24 Month (SCIDT) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from SCID - 24 Month Form | 156 | sas7bdat (448 KB); csv (61.97 KB) | |
Modified ICD-SCID Follow-Up Score Sheet (ICD3) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from Modified ICD-SCID Follow-Up Score Sheet | 242 | sas7bdat (192 KB); csv (25.79 KB) | |
LABS-3 PIBS Enrollment Form (EF3PI) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from LABS-3 PIBS Enrollment Form | 202 | sas7bdat (192 KB); csv (30.63 KB) | |
Childhood Trauma Questionnaire (CTQ) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from Childhood Trauma Questionnaire | 162 | sas7bdat (128 KB); csv (14.9 KB) | |
Psychiatric and Emotional Test Survey - Follow-Up (PETSM) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from Psychiatric and Emotional Test Survey - Follow-Up | 313 | sas7bdat (320 KB); csv (81.64 KB) | |
Demographic Information (DIB) | Demographic Information (DIB) | 63 | sas7bdat (128 KB); csv (5.71 KB) | |
Adult Temperament Questionnaire (ATQ) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from Adult Temperament Questionnaire | 113 | sas7bdat (128 KB); csv (8.41 KB) | |
Pre-Operative Form (PO1) Subset LABS-2 Dataset | Captures data from Pre-Operative Form | sas7bdat (464 KB) | ||
Interpersonal Support Evaluation List (ISEL) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from Interpersonal Support Evaluation List | 101 | sas7bdat (128 KB); csv (6.08 KB) | |
EDE Coding Sheet (EDEC) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from EDE Coding Sheet | 1184 | sas7bdat (7.5 MB); csv (2.27 MB) | |
EDE Coding Sheet Short (EDES) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from EDE Coding Sheet Short | 186 | sas7bdat (1 MB); csv (240.87 KB) | |
Pre-Operative Form (PO1) Subset of LABS-2 Dataset | Captures data from Pre-Operative Form | 202 | csv (123.06 KB) | |
Brief Call (BC) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from Brief Call Form | 2 | sas7bdat (128 KB); csv (935 B) | |
M-FED Baseline (MFEDB) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from M-FED Baseline Form | 202 | sas7bdat (256 KB); csv (51.51 KB) | |
LABS-3 Psychosocial Adverse Event Form (PAE) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from Psychosocial Adverse Event Form | 1 | sas7bdat (128 KB); csv (275 B) | |
Audit (AUD) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from Audit Form | 100 | sas7bdat (128 KB); csv (6.15 KB) | |
M-FED Modified Short (MFEDS) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from M-FED Modified Short Form | 8 | sas7bdat (128 KB); csv (1.26 KB) | |
Demographic Information (DIF) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from Demographic Information Form | 84 | sas7bdat (128 KB); csv (7.03 KB) | |
LABS-3 Off Protocol Form (OFF3) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from Off Protocol Form | 735 | sas7bdat (448 KB); csv (130.63 KB) | |
Nutritional Data System (NDS) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from Nutritional Data System | 6374 | sas7bdat (1.94 MB); csv (1.15 MB) | |
Delayed Discounting - Raw Data (DDRAW) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures delayed discounting raw data | 19113 | sas7bdat (17.89 MB); csv (7.1 MB) | |
Self-Weight Form (WGT) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from Self-Weight Form | 98 | sas7bdat (128 KB); csv (6.52 KB) | |
Psychiatric and Emotional Test Survey - Follow-Up (PETSF) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from Psychiatric and Emotional Test Survey - Follow-Up | 84 | sas7bdat (192 KB); csv (22.07 KB) | |
Impact of Weight Questionnaire (IW) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from Impact of Weight Questionnaire | 248 | sas7bdat (192 KB); csv (24.07 KB) | |
SCID - Annual (30-60 Month) (SCIDA) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from SCID - Annual (30-60 Month) Form | 428 | sas7bdat (784 KB); csv (173.65 KB) | |
Cued Go/No-Go - Summary (GOSUM) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures cued go/no-go summary data | 103 | sas7bdat (128 KB); csv (9.04 KB) | |
M-FED Modified Follow-Up (MFEDF) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from M-FED Follow-Up Form | 1336 | sas7bdat (1.48 MB); csv (358.51 KB) | |
Inactivation Form - LABS-3 (IN3PI) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from Inactivation Form | 27 | sas7bdat (128 KB); csv (1.89 KB) | |
Delayed Discounting - Summary (DDSUM) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures delayed discounting summary data | 103 | sas7bdat (128 KB); csv (7.05 KB) | |
Short Form (SHORT) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from Short Form | 81 | sas7bdat (128 KB); csv (9.02 KB) | |
Impulsive Behavior Scale (UPP) Ancillary Psychosocial Changes Associated with Bariatric Surgery Dataset | Captures data from Impulsive Behavior Scale | 113 | sas7bdat (128 KB); csv (10.04 KB) |
Specimens (4,644)
Specimen | Count |
|---|---|
| Plasma | 2180 |
| Serum | 2113 |
| Urine | 351 |