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NIH: National Institute of Diabetes and Digestive and Kidney Diseases
NIDDK Central Repository
Citation
Warren, J (2015). Maryland Genetics of Interstitial Cystitis Study (MaGIC) (Version 3) [Dataset] NIDDK Central Repository. https://doi.org/10.58020/akda-0m02
Data Availability Statement
Data from Maryland Genetics of Interstitial Cystitis Study (MaGIC) [(Version 3) https://doi.org/10.58020/akda-0m02] reported here are available for request at the NIDDK Central Repository (NIDDK-CR) website, Resources for Research (R4R), https://repository.niddk.nih.gov/.
Acknowledgement Statement
The MaGIC study was conducted by the study investigators and supported by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The resources from the MaGIC (https://doi.org/10.58020/akda-0m02) study reported here were supplied by NIDDK Central Repository (NIDDK-CR) and are available for request at https://repository.niddk.nih.gov. This manuscript was not prepared under the auspices of the MaGIC study and does not necessarily reflect the opinions or views of the MaGIC study, NIDDK-CR, or NIDDK.
Data Package Version
Version 3 (Updated on: Nov 06, 2015)
Resource Availability
  • Data Available for Request
  • Specimens Available for Request
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General Description

The Maryland Genetics of Interstitial Cystitis Study (MaGIC) collected information on several hundred families with two or more blood relatives with interstitial cystitis (IC) to investigate the genetic basis of the condition. The study sought to find genetic variants that are more prevalent in family members who have interstitial cystitis than in those who do not have the disease. Participants who had IC and at least one blood relative with the condition were enrolled. Information was collected via interview by phone, mail, or website.

Objectives

The primary objective of the study was to identify genetic variants associated with IC, with the aim using the genetic information to advance understanding of the cause of the disease.

Eligibility Criteria

The study enrolled participants of 13 years of age or older who had IC or PBS; had at least one relative with IC, PBS, or similar urinary symptoms; were available for an interview by phone, mail, or website; and lived in the US or Canada.

Subjects meeting the above criteria who had Parkinson’s disease, Multiple Sclerosis, Spina bifida, or another neurologic disease that preceded interstitial cystitis symptoms were excluded.

Outcome

Pedigree files based on tracking of IC and related conditions were generated.

Research Area

Urologic Diseases

Study Type

Observational

Study Sites

1

Study Start Date

2004-06

Study End Date

2008-11

Condition

Interstitial Cystitis

Clinical Trials URL

http://www.clinicaltrials.gov/show/NCT00237081

Keywords

Painful Bladder Syndrome (PBS), Family History, Risk Factors, Genetic Variants, Genetics, Pelvic Pain Research, Urogenital Diseases, Interstitial Cystitis (IC)

NIDDK Division

Division of Kidney, Urologic, and Hematologic Diseases

1,526
Participants
Target Population
Children, Adults

Public Documents Table
Document Name
Description
Document Type
File Format
Compliance
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Permitted Use(s) of the Resources
  • Use is allowed for health, medical, or biomedical research purposes
Non-Public Documents (0)
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Datasets (2)
Datasets Table
Dataset Name
Description
# of Records
# of Variables
File Format(s)
Proband Screening Tool Dataset
Contains data collected in the Proband Screening Tool, including age, gender, interstitial cystitis diagnosis, symptoms, treatment history, family history, and eligibility556sas7bdat (176 KB); csv (52.82 KB)
MaGIC Diagnostic Tool Dataset
Contains data collected in the MaGIC Diagnostic Tool, including ethnicity, race, gender, age, urinary frequency, urgency, and pain symptoms, health history and procedures, family history, etc.1526sas7bdat (1.82 MB); csv (555.67 KB)
Specimens (5,691)
Specimens Table
Specimen
Count
DNA842
Urine4849