The Prevention of Lower Urinary Tract Symptoms (PLUS) Research Consortium was established to broaden research efforts beyond the conventional focus on detection and treatment of lower urinary tract symptoms (LUTS). The Consortium prioritizes the promotion and preservation of bladder health as well as the prevention of LUTS among girls and women. While many multi-disciplinary scientific networks focus on pelvic floor dysfunction and LUTS, the PLUS Consortium stands alone in its focus on prevention with researchers from over 50 fields to advance bladder health.