PubMed ID:
24034790
Public Release Type:
Journal
Publication Year: 2014
Affiliation: Department of Clinical Sciences, Lund University, Skåne University Hospital SUS, Malmö, Sweden.
DOI:
https://doi.org/10.1111/pedi.12066
Authors:
Knip M,
Haller MJ,
Veijola R,
Ilonen J,
Toppari J,
Liu S,
Abbondondolo M,
Åberg S,
Adams C,
Agardh D,
Akolkar B,
Akolkar B,
Alejandrino M,
Anderson SW,
Andrén-Aronsson C,
Ask M,
Austin S,
Ayres S,
Barriga K,
Bautista K,
Baxter J,
Becker D,
Beyerlein A,
Bingley P,
Boldison J,
Bonifacio E,
Bourcier K,
Bratrude B,
Bremer J,
Briese T,
Broadhurst J,
Brown R,
Bugawan T,
Burkhardt B,
Butterly J,
Butterworth M,
Carreno G,
Chandler K,
Chen WM,
Cilio C,
Coughlin D,
Crouch CC,
Curnock R,
Cuthbertson D,
Daftary A,
Dalmagro-Elias M,
Davis J,
Easton P,
Eberhard C,
Eisenbarth G,
Elding Larsson H,
Ericson-Hallström E,
Eriksson EA,
Erlich H,
Erlund I,
Farber E,
Fiehn O,
Fiske S,
Foghis G,
Foterek K,
Fowler G,
Franciscus M,
Franco C,
Frank N,
Fransson L,
Gallo D,
Gardiner M,
Gard T,
Geoghan I,
Gerardsson J,
Gesualdo P,
Gesualdo P,
Goode J,
Gowda V,
Hadley D,
Hagopian W,
Hagopian WA,
Haller M,
Hammar C,
Hansen M,
Hansson G,
Hay KM,
Heaney D,
Henneberger L,
Higgins H,
Hoffman M,
Hopkins D,
Hummel M,
Hummel S,
Hyberg S,
Hyöty H,
Ide L,
Järvirova MS,
Jiang N,
Johansen F,
Johnson SB,
Jonasdottir B,
Karban R,
Karlsson EL,
Karlsson UM,
Kersting M,
Ke S,
Killian M,
Kind T,
Knopff A,
Koletzko S,
Krause S,
Krischer J,
Krischer JP,
Larsson HE,
Lee HS,
Lehtonen M,
Leiviskä J,
Lernmark Å,
Lernmark Å,
Lernmark B,
Little RR,
Liu E,
Liu H,
Liu H,
Long A,
Lönnrot M,
Lynch K,
Malloy J,
Månsson-Martinez M,
Mantymaki E,
Marcovina SM,
Marcus P,
Markan M,
Massadakis T,
McCarthy C,
McIndoe R,
McIndoe R,
McLeod W,
Melin J,
Meyer A,
Miao D,
Mulenga D,
Mykkänen J,
Nanto-Salonen K,
Nechtman J,
Nechtman J,
Niininen T,
Nilsson A,
Norris J,
Nyblom M,
Oberste S,
Onengut-Gumuscu S,
Palazoglu M,
Pearson J,
Peplow C,
Petrosino JF,
Pflüger M,
Pickin RR,
Rahmati K,
Reed C,
Rewers M,
Rewers M,
Rich SS,
Ridewood S,
Riikonen A,
Rokni S,
Romo M,
Roth R,
Salminen I,
Samper-Imaz A,
Schatz D,
Schenkel J,
Scott E,
Shankar M,
Sharma A,
She JX,
She JX,
She JX,
Sibthorpe S,
Silvis K,
Simell B,
Simell O,
Simell OG,
Simell T,
Simell V,
Sjöberg B,
Sjöberg M,
Skidmore J,
Smith L,
Smith S,
Stabbert J,
Steck A,
Steed L,
Stenius A,
Stepitova V,
Stock J,
Strauss E,
Sundvall J,
Swartling U,
Tamura R,
TEDDY Study Group,
Tennill AL,
Thomas J,
Törn C,
Triplett E,
Trulsson E,
Uusitalo U,
Varjonen E,
Vehik K,
Vehik K,
Virtanen SM,
Wallin A,
Warncke K,
Washington E,
Waugh K,
Wikoff B,
Williams A,
Williams J,
Williams N,
Wimar Å,
Winkler C,
Wohlgemuth G,
Wong J,
Wyatt R,
Yang J,
Yan X,
Yu L,
Zhao Y,
Ziegler A,
Ziegler AG
Studies:
The Environmental Determinants of Diabetes in the Young
The Environmental Determinants of Diabetes in the Young (TEDDY) study is designed to identify environmental exposures triggering islet autoimmunity and type 1 diabetes (T1D) in genetically high-risk children. We describe the first 100 participants diagnosed with T1D, hypothesizing that (i) they are diagnosed at an early stage of disease, (ii) a high proportion are diagnosed by an oral glucose tolerance test (OGTT), and (iii) risk for early T1D is related to country, population, human leukocyte antigen (HLA)-genotypes and immunological markers.