PubMed ID:
23657799
Public Release Type:
Journal
Publication Year: 2013
Affiliation: Institute of Diabetes Research, Helmholtz Zentrum München and Forschergruppe Diabetes, Klinikum rechts der Isar, Technische Universität München, Ingolstädter Landstrasse 1, 85764, Neuherberg, Germany.
DOI:
https://doi.org/10.1007/s00125-013-2924-y
Authors:
Akolkar B,
Bonifacio E,
Briese T,
Hagopian W,
Hyoty H,
Krischer J,
Lee HS,
Lernmark Å,
Pflueger M,
Rewers M,
She JX,
Simell O,
TEDDY study group,
Winkler C,
Ziegler AG
Studies:
The Environmental Determinants of Diabetes in the Young
Viruses are candidate causative agents in the pathogenesis of autoimmune (type 1) diabetes. We hypothesised that children with a rapid onset of type 1 diabetes may have been exposed to such agents shortly before the initiation of islet autoimmunity, possibly at high dose, and thus study of these children could help identify viruses involved in the development of autoimmune diabetes.