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Publication Information

PubMed ID
Public Release Type
Journal
Publication Year
2011
Affiliation
Department of Pediatrics, Skåne University Hospital, Lund University, Malmö, Sweden, helena.larsson@med.lu.se
Authors
Bell R, Dabelea D, Dolan L, DPV Study Group, Elding Larsson H, Finnish Diabetes Registry Study Group, Haller MJ, Holl R, Knip M, Lindblad B, Pihoker C, Samuelsson U, SEARCH Study Group, Swediabkids Study Group, TEDDY Study Group, Vehik K, Veijola R
Studies
Citation
Elding Larsson H, Vehik K, Bell R, Dabelea D, Dolan L, Pihoker C, Knip M, Veijola R, Lindblad B, Samuelsson U, Holl R, Haller MJ, TEDDY Study Group, SEARCH Study Group, Swediabkids Study Group, DPV Study Group, Finnish Diabetes Registry Study Group. Reduced prevalence of diabetic ketoacidosis at diagnosis of type 1 diabetes in young children participating in longitudinal follow-up. Diabetes Care 2011 Nov;34(11):2347-52. Epub 2011 Oct 4.

Abstract

Young children have an unacceptably high prevalence of diabetic ketoacidosis (DKA) at the clinical diagnosis of type 1 diabetes. The aim of this study was to determine whether knowledge of genetic risk and close follow-up for development of islet autoantibodies through participation in The Environmental Determinants of Diabetes in the Young (TEDDY) study results in lower prevalence of DKA at diabetes onset in children aged <2 and <5 years compared with population-based incidence studies and registries.