The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) has established the Drug-Induced Liver Injury Network (DILIN) to collect and analyze cases of severe liver injury caused by prescription drugs, over-the-counter drugs, and alternative medicines, such as herbal products and supplements. The diagnosis of drug-induced liver injury relies on evidence linking the injury to a specific drug or agent. DILIN uses expert opinion to determine the degree of association between the implicated medication(s) and the liver injury.