Hepatitis B Research Network (HBRN)

General Description

The Hepatitis B Research Network (HBRN) is an NIDDK-funded network of 28 Clinical Sites, and Immunology Center and a Data Coordinating Center (DCC). The goals of the network are to study the natural history, pathogenesis, diagnosis and treatments of chronic hepatitis B in children and adults. The HBRN has implemented a longitudinal observational database of children 2-17 years, a longitudinal observational database of adults at least 18 years of age, and three treatment trials for chronic hepatitis B in adults and children.

Related Studies

Acronym	Name
HBRN Immune Tolerant P	Clinical Trial of Entecavir/Pegylated Interferon in Immune Tolerant Children with Chronic Hepatitis B Virus Infection
HBRN Immune Tolerant A	Combination Entecavir and Peginterferon Therapy in HBeAg-Positive Immune-Tolerant Adults with Chronic Hepatitis B
HBRN Immune Active	Combination Therapy of Peginterferon Alfa-2a and Tenofovir versus Tenofovir Monotherapy in HBeAg-positive and HBeAg-negative Chronic Hepatitis B
HBRN Cohort A	Hepatitis B Research Network Adult Cohort Study
HBRN Cohort P	Hepatitis B Research Network Pediatric Cohort Study
HBRN Immunology Treatment	Immune Regulation and Costimulation in Natural History and Therapeutic Outcome of Chronic Hepatitis B
HBRN Immunology Cohort	Immune Regulation and Costimulation in Natural History of Chronic Hepatitis B
HBRN HIV Co-Infection	Observational Study of Hepatitis B Virus (HBV) in Patients Co-Infected with Human Immunodeficiency Virus (HIV)