Vuppalanchi R, Deppe RB, Yates KP, Comerford M, Masuoka HC, Tetri BA, Loomba R, Brunt E, Kleiner DE, Tonascia J, Chalasani NP. Changes in Serum Cytokeratin 18 Levels Significantly Predict Changes in Liver Histology in Adults With Nonalcoholic Steatohepatitis: Results From the Pivens Trial. Gastroenterology 2013 May;144(Issue 5, Supplement 1):S-951. |
Nelson JE, Belt PH, Wilson L, Yeh MM, Tetri BA, Chalasani N, Sanyal A, Kowdley K. Elevated Serum Ferritin Values Above the Upper Limit of Normal Are Associated With Laboratory and Histologic Evidence of Increased NASH Severity, but Not the Presence of Diabetes or Metabolic Syndrome Among Patients in the NASH CRN. Gastroenterology 2011 May;140(Issue 5, Supplement 1):S727. |
Athinarayanan S, Wei R, Zhang M, Bai S, Traber MG, Yates K, Cummings OW, Molleston J, Liu W, Chalasani N. Genetic polymorphism of cytochrome P450 4F2, vitamin E level and histological response in adults and children with nonalcoholic fatty liver disease who participated in PIVENS and TONIC clinical trials. PLoS One 2014 Apr 23;9(4):e95366. doi: 10.1371/journal.pone.0095366. eCollection 2014. |
Brunt EM, Kleiner DE, Wilson L, Unalp A, Tonascia J, Neuschwander-Tetri BA. Histologic Predictors of Improvement in Fibrosis in NASH: Results from the Clinical Research Network PIVENS Trial. Hepatology 2012 Oct;56(Supplement S1):887A. |
Cheng J, Joyce A, Sanyal AJ. Metabolomic Profiling to Define Predictors of Response to Vitamin E for Non- Alcoholic Steatohepatitis (NASH). Gastroenterology 2011 May;140(Issue 5, Supplement 1):S903-S904. |
Chalasani NP, Sanyal AJ, Kowdley KV, Robuck PR, Hoofnagle J, Kleiner DE, Unalp A, Tonascia J, NASH CRN Research Group. Pioglitazone versus vitamin E versus placebo for the treatment of non-diabetic patients with non-alcoholic steatohepatitis: PIVENS trial design. Contemp Clin Trials 2009 Jan;30(1):88-96. Epub 2008 Sep 10. |
Sanyal AJ, Chalasani N, Kowdley KV, McCullough A, Diehl AM, Bass NM, Neuschwander-Tetri BA, Lavine JE, Tonascia J, Unalp A, Van Natta M, Clark J, Brunt EM, Kleiner DE, Hoofnagle JH, Robuck PR, NASH CRN. Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis. N Engl J Med 2010 May 6;362(18):1675-85. Epub 2010 Apr 28. |
Cheng J, Joyce A, Yates KP, Sanyal AJ. Response to Vitamin E for Non-Alcoholic Steatohepatitis (NASH): What Is the Mechanism? Gastroenterology 2013 May;144(Issue 5, Supplement 1):S-1012. |
Guy CD, Suzuki A, Abdelmalek MF, Burchette JL, Diehl AM, NASH CRN. Treatment response in the PIVENS trial is associated with decreased Hedgehog pathway activity. Hepatology 2015 Jan;61(1):98-107. Epub 2014 Aug 25. |